context hepatitis b virus (hbv) and hepatitis c virus (hcv) infections constitute a major global health problem. about 60,000 and 350,000 deaths occur as the results of hbv and hcv infections, respectively. chronic hepatitis b and c infections are leading causes of cirrhosis and hepatocellular carcinoma (hcc) which are considered as the third cancer-associated cause of deaths worldwide. iran su...

High-intensity focused ultrasound (HIFU) has been shown to be a valuable tool in the management of small liver tumors such as hepatocellular carcinoma (HCC). It safe and effective means ablate HCC even presence advanced cirrhosis. This review examines challenges faced during HIFU ablation when target are located difficult locations dome, close rib cage, near large blood vessels or heart, adjace...

It has come to our attention that the excel files of following supplementary tables were not included during online publication article: Table S3, S4, S8, S9, S13, and S14. These have now been made available online. We apologize for any inconvenience caused. Molecular characterisation hepatocellular carcinoma in patients with non-alcoholic steatohepatitisJournal HepatologyVol. 75Issue 4PreviewN...

: In this short commentary, we discuss the most important risk factors for liver cancer. One of the most striking risks is infection with hepatitis B and C viruses, leading to chronic hepatitis, which may later develop into hepatocellular carcinoma (HCC). The use of alcohol may lead to cirrhosis, which is scarring the liver, is associated with 30 a more increase in HCC and 10-20 times more incr...

Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver worldwide. The incidence of HCC is increasing in North America secondary to rises in chronic liver disease from alcohol abuse and viral hepatitis. HCC most commonly metastasizes hematogenously or through lymphatics to the lungs and regional lymph nodes. Involvement of small bowel is rare and typically results from dire...

Portal vein tumor thrombus (PVTT) in hepatocellular carcinoma (HCC) is a common entity. However, the prognosis of patients with hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) is extremely poor. The current study reports a case of HCC with PVTT, including a description of the gross surgical pathology and discussion of the relevance of assessing the growth of the tumor thro...

Objective(s): Although low-dose radiotherapy (RT) that involves low collateral damage is more suitable for hepatocellular carcinoma (HCC) than traditional high-dose RT, but to achieve satisfactory therapeutic effect with low-dose RT, it is necessary to sensitize HCC cells to irradiation. This study was aimed to determine whether radiosensitivity of HCC cells can be enhanced using miR-26b by tar...

BACKGROUND In the spectrum of molecular alterations found in hepatocellular carcinoma (HCC), somatic mutations in the WNT/β-catenin pathway and the p53/cell cycle control pathway are among the most frequent ones. It has been suggested that both mutations occur in a mutually exclusive manner and they are used as molecular classifiers in HCC classification proposals. CASE PRESENTATION Here, we ...

Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare variant of hepatocellular carcinoma, usually presenting in the younger population (<40 years) without underlying liver disease. Although it has a better prognosis than hepatocellular carcinoma, it has a high rate of recurrence months to years after primary resection. While sites of recurrence usually involve the liver, regional lymph nod...

Hepatocellular carcinoma (HCC) is a common malignancy and cause of death in the developing world. In this report, a case of obstructive jaundice caused by hepatocellular carcinoma with bile duct tumor thrombi is presented.