Neurons have two types of processes: axons and dendrites. Axons have an active disassembly program activated by severing. It has not been tested whether dendrites have an analogous program. We sever Drosophila dendrites in vivo and find that they are cleared within 24 h. Morphologically, this clearance resembles developmental dendrite pruning and, to some extent, axon degeneration. Like axon de...

Searching for a general and technically simple multi-scale formalism to treat interacting fermions, we develop a (Wilson-Kadanoo) block renormalization group mechanism, which, due to the property of \orthogonality between scales", establishes a trivial link between the correlation functions and the eeective potential ow, leading to simple expressions for the generating and correlation functions...

Higher general intelligence attenuates age-associated cognitive decline and the risk of dementia. Thus, intelligence has been associated with cognitive reserve or resilience in normal aging. Neurophysiologically, intelligence is considered as a complex capacity that is dependent on a global cognitive network rather than isolated brain areas. An association of structural as well as functional br...

A century ago, Peirce developed a pragmatic theory of meaning. The theory appeals to the Pragmatic Maxim. It says that the meaning of a concept is the sum total of its implications for possible observations and actions. The Relevance Theory of Sperber & Wilson is classified according to that criteria to the category of pragmatic theories of meaning. It is argued that relevance is an instance of...

'Traumatic Epilepsy after Closed Head Injury. Gilbert P nstration of-82BR in Nerve Cells. Sven-Olof Brattgirdat -Frontal Lobe Wounds Causing Disinhibition. A Study of Six Cases. Hugh F. Jarvie 14 AHistological and Chemical Study of Three Cases of Diffuse Cerebral Sc(erosis. W. Blackwood and J. N. Cumings .. .. .. .. .. .. 33 oPst-encephalitic Parkinsonism with Amyotrophy. J. G. Greenfield and W...

When Policy Topic is covered A number of indications for chelation therapy have received Food and Drug Administration (FDA) approval and for which chelation therapy is considered standard of care treatment. They include:  extreme conditions of metal toxicity;  treatment of chronic iron overload due to blood transfusions (transfusional hemosiderosis) and due to non-transfusion-dependent thalas...

AIM The authors compared the incidence of radiologically documented and/or symptomatic adjacent segment degeneration in and between patients who underwent anterior or posterior single-level, simple discectomy. MATERIAL AND METHODS 79 patients were clinically and radiologically examined for adjacent segment degeneration (ASD). The results were compared to evaluate which approach was predominan...

At the beginning of the 1990s, as part of work being done for a master's degree thesis in physics, an important observation of hippocampal degeneration in Alzheimer's disease was made in Pavia. However this result was never published in a full scientific paper. This case gives an idea of how an isolated observation can, in the right setting, develop into a real scientific achievement.

A 42-year-old man had Intacs (Addition Technology Inc.) implantation for early pellucid marginal degeneration (PMD). Two Intacs segments (0.45 mm thickness) were inserted uneventfully in the fashion typically used for low myopia correction (nasal-temporal). Eleven months after the procedure, the uncorrected visual acuity was 20/200, compared with counting fingers preoperatively, while the best ...