BACKGROUND To compare the safety and efficacy of loteprednol etabonate ophthalmic ointment 0.5% (LE ointment), a new topical ointment formulation, with vehicle for the treatment of inflammation and pain following cataract surgery. METHODS Two randomized, multicenter, double-masked, parallel-group, vehicle-controlled studies were conducted. Patients aged ≥18 years with a combined postoperative...

Purpose: The purpose of this study is to investigate the healing impact an ointment derived from Alkanna tinctoria plant upon Pseudomonas aeruginosa-induced infections. 
 Material and Methods: In study, 18 male adolescent rats (mean age 6 weeks) weighed average 180 g were used. Animals divided into 3 groups. Group 1: Control group (consisting burns, no treatment was done), 2 (P. aeruginosa...

A 60% (W/W) simple ointment of Udumbar (Ficus glomeruta) was prepared. The cases of cervical erosion were selected from S.S. Hospital, Institute of Medical Sciences, Banaras Hindu University, Varanasi. The ointment was applied in the form of tampon following electric cauterization and compared the results with the triples sulpha ointment. It showed 95% cure rate as against 85% of Triple sulpha ...

BACKGROUND Oronine H(®) ointment, which contains chlorhexidine gluconate as its active component, is a well known disinfectant, and has been widely used for treatment of acne in Japan. In this study, we investigated the inhibitory effect of this ointment on the formation of comedones induced by application of 50% oleic acid on the orifices of the external auditory canals of rabbits. METHODS T...

Background: Wound healing is a physiologic process that cells and tissues react when the skin exposed to thermal injury. The inflammatory has ‎essential effects on wound includes coordination between immunological biological responses. Chemical herbal medicines are locally or systemically administrated help healing. Herbal have become more prevalent in recent years due fewer side effects. Dwarf...

Recently, numerous compounds have been studied in order to develop antibacterial agents, which can prevent colonized wounds from infection, and assist the wound healing. For this purpose, novel silver chloride nanoparticles stabilized with chitosan oligomer (CHI-AgCl NPs) were synthesized to investigate the influence of antibacterial chitosan oligomer (CHI) exerted by the silver chloride nanopa...

Comparative antimicrobial activity of four ointments, i. e. stellanin-PEG, levomecole, dioxydin 5% ointment and betadin was studied with the use of collection microbial strains and the most frequent pathogens of pyoinflammary processes in surgical patients. Clinical strains of gram positive and gram negative organisms were used as the test cultures. Stellanin-PEG 3% ointment showed high antimic...

In vitro release characteristics of prednisolone (PD) and its ƒÀand ƒÁ-cyclodextrin (ƒÀand ƒÁCyD) complexes were investigated by using an ointment release simulator with artificial doublelayer membranes. The release of PD from hydrophilic ointment was significantly improved by ƒÀand ƒÁ-CyD complexations. Permeation and uptake studies indicated that the enhanced release of PD from the ointment m...