نتایج جستجو برای: hesi
تعداد نتایج: 107 فیلتر نتایج به سال:
BACKGROUND The U.S. EPA revised the Reproduction and Fertility Effects Test Guideline (OPPTS 870.3800/OECD 416) in 1998, adding numerous endpoints in an effort to incorporate new methodologies, improve the sensitivity for detecting reproductive toxicants, and more efficiently utilize study animals. Many of these new endpoints have not been used in regulatory reproductive toxicology studies prio...
CEBS (Chemical Effects in Biological Systems) is an integrated public repository for toxicogenomics data, including the study design and timeline, clinical chemistry and histopathology findings and microarray and proteomics data. CEBS contains data derived from studies of chemicals and of genetic alterations, and is compatible with clinical and environmental studies. CEBS is designed to permit ...
The ILSI Health and Environmental Sciences Institute (HESI) has developed a framework to support a transition in the way in which information for chemical risk assessment is obtained and used (RISK21). The approach is based on detailed problem formulation, where exposure drives the data acquisition process in order to enable informed decision-making on human health safety as soon as sufficient ...
Many metabolomics studies use mixtures of (acidified) methanol and water for sample extraction. In the present study, we investigated if the extraction with methanol can result in artifacts. To this end, wheat leaves were extracted with mixtures of native and deuterium-labeled methanol and water, with or without 0.1% formic acid. Subsequently, the extracts were analyzed immediately or after sto...
Petroliotik eratorritako plastikoen produkzioa gero eta handiagoa da, bestelako materialekin konparatuz, material oso moldakorrak direlako. Hori dela eta, plastikoak aplikazio ugaritan aurki ditzakegu, adibidez, eguneroko bizitzan polibinil kloruroa taperretan daukagu edo politetrafluoroetilenoa (PTFE) medikuntzako kateterretan. Produzitzen diren plastiko guztien artean, Europar Batasunak (EBk)...
Abstract. Analysing the composition of ambient ultrafine particles (UFPs) is a challenging task due to low mass and chemical complexity small particles, yet it prerequisite for identification particle sources assessment potential health risks. Here, we show molecular characterization UFPs, based on cascade impactor (Nano-MOUDI) samples that were collected at an air quality monitoring station ne...
Abstract. Atmospheric oxidation chemistry and, more specifically, photooxidation show that the long-term of organic aerosol (OA) progressively erases initial signature chemical compounds and can lead to a relatively uniform character oxygenated (OOA). This uniformity observed after long reaction time seems contrast with great diversity mechanisms in early stages oxidation. The numerous studies ...
Background: Mental distress among medical students is often reported. Burnout has not been studied frequently and studies using interviewer-rated diagnoses as outcomes are rarely employed. The objective of this prospective study of medical students was to examine clinically significant psychiatric morbidity and burnout at 3rd year of medical school, considering personality and study conditions ...
ARIOUS WORKERS have teported experiniemstal amid clinical ohset-s-atiomss which suggested that psychological stress might affect the blood coagulation system. As early as 1771 William Hesi-somi msoted hypercoagulability of the blood follosvcd hemorrhage. In 1903 Vosburgh amid Richards29 observed misom e iapid (‘0agulatioms accompanied ami imicrease ins the blood sugar of dogs receis-imsg adtemi...
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