BACKGROUND From fundamental studies to industrial processes, synthesis of heterologous protein by micro-organisms is widely employed. The secretion of soluble heterologous proteins in the extracellular medium facilitates their recovery, while their attachment to the cell surface permits the use of the recombinant host cells as protein or peptide supports. One of the key points to carry out hete...

It is possible to use transgenic plants, as bioreactors, for the production of recombinant inexpensive chemicals and drug components. Transient gene expression is an appropriate alternative to stable transformation because it allows an inexpensive and rapid method for expression of recombinant proteins in plant tissues. In recent years, plant viral vectors have been increasingly developed as su...

in a series of heterologous immunity studies s. haematobium, s. bovis and o. turkestanicum in calves, a large number of s. haematobium cercariae (21,000 cercariae) were used repeatedly as the immunization agent. at autopsy, 22 weeks after initial exposure, immature s. haematobium was detected. thirteen weeks after initial exposure a group of calves was challenged with s. bovis and another group...

Clinical manifestations of viral infections are highly variable, both in type and severity, among individual patients. Differences in host genetics and in dose and route of infection contribute to this variability but do not fully explain it. New studies now show that each subject's history of past infections individualizes the memory T cell pool. Private T cell receptor specificities of these ...