نتایج جستجو برای: heterozygosity
تعداد نتایج: 9512 فیلتر نتایج به سال:
During meiosis homologous chromosomes undergo crossover recombination. Sequence differences between homologs can locally inhibit crossovers. Despite this, nucleotide diversity and population-scaled recombination are positively correlated in eukaryote genomes. To investigate interactions between heterozygosity and recombination we crossed Arabidopsis lines carrying fluorescent crossover reporter...
The detection of loss of heterozygosity, indicative of the presence of a tumor suppressor gene, has been reported to occur frequently on chromosome 22q in human ovarian cancer. In this study, 110 sporadic ovarian tumors were analyzed using 8 polymorphic loci to define a minimum region of loss. Fifty-eight (53%) tumors showed loss of heterozygosity, and of these 6 exhibited partial loss, enablin...
The authors studied the genetic diversity of reproductive nucleus mini-pigs at Institute Cytology and Genetics (IC&G) Siberian Branch Russian Academy Sciences (SB RAS). To do this, used indicators individual homo- heterozygosity, calculated based on «blood fractions» large small forms domestic pigs, initial for breeding group. study showed that average value heterozygosity (conditionally ac...
s.c. and abdominal tumors from interspecific hybrid, transgenic mice containing the SV40 early region linked to a renin enhancer/promoter were analyzed for loss of heterozygosity to identify chromosomal regions involved in tumorigenesis. A very high frequency of loss of heterozygosity/partial loss of heterozygosity or allelic imbalance involving the distal regions of chromosome 8 was observed i...
Allozyme analysis was used to assess genetic variability in tephritid fruit fly Bactrocera diversa and B. zonata. In our experimental conditions, allozyme analysis at twelve enzyme loci scores twenty one putative alleles. The amount of mean observed heterozygosity (HO) was 0.22 and 0.28 and amount of mean expected heterozygosity (HE) was 0.28 and 0.37, in B. diversa and B. zonata, respectively....
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