Objective(s):Lipopolysaccharide (LPS)-induced endotoxemia is known to cause male infertility. This study was designed to explore the effects of bacterial LPS on histomorphometric changes of mice testicular tissues.    Materials and Methods: In experiment 1, a pilot dose responsive study was performed with mice that were divided into five groups, receiving 36000, 18000, 9000, and 6750 µg/kg body...

Patients with osteoporosis-associated WNT1 or PLS3 mutations have unique bone histomorphometric features and osteocyte-specific hormone expression patterns. To investigate the effects of on material properties. Transiliac biopsies were evaluated by quantitative backscattered electron imaging, immunohistochemistry, histomorphometry. Ambulatory patients. Three pediatric eight adult patients mutat...

CONTEXT Data on vascular alterations in patients with hepatosplenic schistosomiasis and portal hypertensive colopathy and changes in these after surgery to decrease portal hypertension are limited. OBJECTIVE The purpose of this study was to analyse the alterations of portal hypertensive colopathy previously and 6-12 months after splenectomy and gastric devascularization. METHODS Twelve pati...

There is increasing interest in the discovery of natural compounds that could favorably affect the skeletal system. Curcumin is a constituent of turmeric, a plant which has been used for centuries as a dietary spice and a traditional Indian medicine. Curcumin has been reported to affect differentiation, activity and the lifespan of osteoblasts and osteoclasts in vitro. The aim of the present st...

Assessment of morphological changes has more often been used in the diagnosis and assessment of intestinal pathology and development. Since methionine is widely used in nutritional and sports supplements and also there is not enough information about the effect of this amino acid on the gastrointestinal histomorphometry, the aim of this study was to assess the effect of methionine on the small ...

The rabbit is the smallest and least expensive laboratory animal in which serial semen samples can be obtained for morphologic, biochemical, and fertility evaluation. The female rabbit has a predictable reproductive cycle and can be artificially inseminated with a known amount of sperm during fertility testing. These advantages make the rabbit an extremely valuable model for studying the effect...

PURPOSE To compare histological changes induced by antiglaucoma medications in the rabbit conjunctiva. METHODS Fifty New Zealand rabbits were divided in 5 groups of 10 animals. The left eyes were treated daily with one drop of bimatoprost 0.03%, travoprost 0.004%, latanoprost 0.005%, timolol maleate 0.5% or artificial tears containing benzalkonium chloride (BAK) for 30 days. The right eyes se...

To elucidate the mandibular morphological changes due to occlusal and masticatory alterations in addition to aging, 66 Donryu male rats (30-74 weeks old) were divided into three groups, the control group (solid diet), the soft diet group (powder diet containing the same components as the solid one from the 43rd week) and the molarless group (all molars were removed at 43 weeks and then fed a po...

Bone microstructure has usually been assessed by obtaining samples invasively and analyzing them with conventional histomorphometric methods. Improvements in high-resolution image acquisition systems have enabled non-invasive assessment of bone morphology and a more precise 3-D evaluation by means of "virtual biopsies", permitting bone assessment in regeneration or remodeling processes. This re...

objective(s): the aim of this study was to observe the influence of phytoestrogen α-zearalanol on ovariectomy-induced postmenopausal osteoporosis in rats. materials and methods:40 sd female rats were randomly divided into four groups: sham group, ovx group (ovariectomized and fed estrogen), α-zearalanol group (ovariectomized and fed α-zearalanol) and untreated group (ovariectomized). three week...