self-determination theory (sdt) states that satisfaction of basic psychological needs, including the need for autonomy, competence and relatedness will lead to intrinsic motivation. this study examines the relationship between basic psychological needs and intrinsic motivation of iranian female students in mathematics. for this purpose, 382 students of five school responded to the scale of intr...

Insulin-like growth factors (IGFs) are important regulators of the activity of mature osteoblasts, but their effects on osteoprogenitor cells in human bone marrow stroma are unclear. In this study, we assessed the effects of IGFs on a conditionally immortalized human marrow stromal cell line, hMS(3-4), which has the ability to differentiate to either mature osteoblasts or adipocytes. hMS(3-4) c...

Heavy metals (HMs) in sewage sludge have become the crucial limiting factors for land use application. Samples were collected and analyzed from 32 waste water treatment plants (WWTPs) in the Shanxi Province, China. HM levels in sewage sludge were assessed. The multivariate statistical method principal component analysis (PCA) was applied to identify the sources of HMs in sewage sludge. HM pollu...

Gestational trophoblastic disease (GTD) is a group of conditions that originate from the abnormal proliferation of trophoblastic cells. GTDs encompass hydatidiform moles (HMs) and gestational trophoblastic neoplasia (GTN). GTNs are a group of malignant diseases that require chemotherapy, or more aggressive treatment. There is a requirement for more tumor markers to predict the development of GT...

Hydroxymandelate synthase (HMS) catalyzes the committed step in the formation of para-hydroxyphenylglycine, a recurrent substructure of polycyclic non-ribosomal peptide antibiotics such as vancomycin. HMS uses the same substrates as 4-hydroxyphenylpyruvate dioxygenase (HPPD), 4-hydroxyphenylpyruvate (HPP) and O(2), and also conducts a dioxygenation reaction. The difference between the two lies ...

Middle East respiratory syndrome coronavirus (MERS-CoV) is continuously spreading and causing severe and fatal acute respiratory disease in humans. Prophylactic and therapeutic strategies are therefore urgently needed to control MERS-CoV infection. Here, we generated a humanized monoclonal antibody (mAb), designated hMS-1, which targeted the MERS-CoV receptor-binding domain (RBD) with high affi...

Time–delay artificial neural network (ANN) single layer and multilayer artificial models were developed for predicting the shelf life of processed cheese stored at 7-8o C. Soluble nitrogen, pH; standard plate count, yeast & mould count, and spore count were input variables, and sensory score was output variable. The results showed excellent agreement between training and validation data with hi...

The paper discusses the complex, agent-oriented hierarchic memetic strategy (HMS) dedicated to solving inverse parametric problems. The strategy goes beyond the idea of two-phase global optimization algorithms. The global search performed by a tree of dependent demes is dynamically alternated with local, steepest descent searches. The strategy offers exceptionally low computational costs, mainl...

Inhibitory synaptic inputs to hypoglossal motoneurons (HMs) are important for modulating excitability in brainstem circuits. Here we ask whether reduced inhibition, as occurs in three murine mutants with distinct naturally occurring mutations in the glycine receptor (GlyR), leads to intrinsic and/or synaptic homeostatic plasticity. Whole cell recordings were obtained from HMs in transverse brai...

Andréia Gomes Bezerraa,*, Giuseppina Negria,d, Joaquim Maurício Duarte-Almeidab,d, Soraya Soubhi Smailic and Elisaldo Araújo Carlinid Departamento de Psicobiologia, Universidade Federal de São Paulo, 04023-062 São Paulo – SP, Brasil Laboratório de Farmacognosia e Produtos Naturais, Universidade Federal de São João del-Rei, 35501-296 Divinópolis – MG, Brasil Departamento de Farmacologia, Univers...