We use some BRS techniques to construct Chern-Simons forms generalizing the Chern character of K1 groups in the Cuntz-Quillen description of cyclic homology. MSC91: 19D55, 81T13, 81T50

background: acanthamoeba castellanii is the important cause of amoebic keratitis in iran. the key molecule in pathogene­sis of acanthamoeba keratitis is mannose binding protein (mbp) led to adhesion of amoeba to corneal epithelium. subse­quent to adhesion other cytopathic effects occur. the goal of this study was to identify the molecular characterization of a gene encoding mbp in an iranian is...

Inference of homology from protein sequences provides an essential tool for analyzing protein structure, function, and evolution. Current sequence-based homology search methods are still unable to detect many similarities evident from protein spatial structures. In computer science a search engine can be improved by considering networks of known relationships within the search database. Here, w...

Homologous recombination plays pivotal roles in DNA repair and in the generation of genetic diversity. To locate homologous target sequences at which strand exchange can occur within a timescale that a cell's biology demands, a single-stranded DNA-recombinase complex must search among a large number of sequences on a genome by forming synapses with chromosomal segments of DNA. A key element in ...

Smith Waterman Algorithm[1] is an efficient and useful algorithm for homology search problems. However, it can not be processed within reasonable time on desktop computer systems, therefore, dedicated hardware systems which is very expensive are used in general. In this paper, we propose a homology search system with reconfigurable hardware. For reducing the cost, the system is composed of off-...

The growing interest in genomic research has caused an explosive growth in the size of DNA databases making it increasely challenging to perform searches on them. In this paper, we proposed an index structure called the ed-tree for supporting fast and effective homology searches on DNA databases. The ed-tree is developed to enable probe-based homology search algorithms like Blastn which generat...

In E. coli homologous recombination, a filament of RecA protein formed on DNA searches and pairs a homologous sequence within a second DNA molecule with remarkable speed and fidelity. Here, we directly probe the strength of the two-molecule interactions involved in homology search and recognition using dual-molecule manipulation, combining magnetic and optical tweezers. We find that the filamen...

Already proposed a new vision, a heuristic based on a modern branch of biology called Biotechnology. "This is any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use" [SCDB, 1992]. For individuals who have undergone any change in their genes through biotechnology techniques are known as Transg...

The large numbers of protein sequences generated by whole genome sequencing projects require rapid and accurate methods of annotation. The detection of homology through computational sequence analysis is a powerful tool in determining the complex evolutionary and functional relationships that exist between proteins. Homology search algorithms employ amino acid substitution matrices to detect si...