introduction 3d reconstruction of an object from its 2d cross-sections (slices) has many applications in different fields of sciences such as medical physics and biomedical engineering. in order to perform 3d reconstruction, at first, desired boundaries at each slice are detected and then using a correspondence between points of successive slices surface of desired object is reconstructed. mate...

Prenatal organophosphate exposure elicits long-term brain cytoarchitecture and cognitive function impairments, but the mechanism underlying the onset and development of neural progenitors remain largely unclear. Using precise positioned brain slices, we observed an alternated cleavage plane bias that emerged in the mitotic neural progenitors of embryonal neocortex with diazinion (DZN) and chlor...

Neocortical neurons in vivo receive concurrent synaptic inputs from multiple sources, including feedforward, horizontal, and feedback pathways. Layer 2/3 of the visual cortex receives feedforward input from layer 4 and horizontal input from layer 2/3. Firing of the pyramidal neurons, which carries the output to higher cortical areas, depends critically on the interaction of these pathways. Here...

Layer I is a dense synaptic zone ubiquitous in cerebral cortex. Here we describe a novel in vitro preparation of rat somatosensory (SI) neocortical slices that isolates the fibers that extend horizontally through layer I, and allows intracellular and extracellular analysis of synaptic input to dendrites in layer I. Current source-density analysis of this isolated horizontal layer I input reveal...

A method for simultaneous multislice imaging is presented that uses a multislice RF pulse that imparts a different linear phase profile to each slice. During readout, slices are unaliased by using extra slice-select gradient lobes, which rephase and dephase individual slices one at a time. Compared to other simultaneous slice methods, this method avoids distortion by slice-select gradients, and...

We show that carbenoxolone, a drug used to block hemichannels in the retina to test the ephaptic model of horizontal cell inhibitory feedback, has strong inhibitory effects on voltage-gated Ca channels. Carbenoxolone (100 microM) reduced photoreceptor-to-horizontal cell synaptic transmission by 92%. Applied to patch-clamped, isolated cone photoreceptors, carbenoxolone inhibited Ca channels with...

We develop a mathematical model of a large-scale cracked Horizontal Axis Wind Turbine (HAWT) describing the flapping flexure of the flexible tower and blades. The proposed model has enough fidelity to be used in health monitoring applications. The equations of motion account for the effect of the applied aerodynamic forces, modeled using the Blade Element Momentum (BEM) theory, and the location...

A self-correction method for the drift artifacts of laboratory cone-beam nanoscale X-ray computed tomography (nano-CT) based on trajectory projection centroid (TPC) is proposed. This does not require additional correction phantoms, simplifying process. The whole TPC estimated by partial in optimal set. calculated measured and TPC. interval search used so that proposed can adapt to case a trunca...

In the case of Roşia Poieni open pit mine level +805 m was established as a daily operating limit; division into benches based on this by dividing horizontal slices with thickness 15 m, equal to height bench. Thus, there were 27 in Curmătura area and 23 Ruginiş area. The general slope angle set at 35°, for which tailings volumes implicitly opening-up coefficient calculated. stability analysis p...