نتایج جستجو برای: humans 19th chromosome

تعداد نتایج: 310799  

Journal: :Cell 2010
Shijing Luo Gunnar A. Kleemann Jasmine M. Ashraf Wendy M. Shaw Coleen T. Murphy

Reproductive cessation is perhaps the earliest aging phenotype that humans experience. Similarly, reproduction of Caenorhabditis elegans ceases in mid-adulthood. Although somatic aging has been studied in both worms and humans, mechanisms regulating reproductive aging are not yet understood. Here, we show that TGF-β Sma/Mab and Insulin/IGF-1 signaling regulate C. elegans reproductive aging by m...

2014
Chen Ning Yang

Coulomb, Carl Friedrich Gauss, André Marie Ampère, and Michael Faraday discovered the four experimental laws concerning electricity and magnetism, James Clerk Maxwell added the displacement current and thereby created the great set of Maxwell’s equations. That view is not entirely wrong, but it obscures the subtle interplay between sophisticated geometrical and physical intuitions that led not ...

بهلکه, گلدی محمد, بیابانی, عباس, صبوری, حسین, فلاحی, حسینعلی,

In order to study the effect of planting date on five cultivars of wheat (Khazar1, Falat, Zagros, Kohdasht, Karim) an experiment was conducted as a split-plot randomized complete block in Research Farm of Gonbad Kavous University, Gonbad Kavous, in northern Iran at 2013-2014. Main plots contained nine planting dates (November 4th, November 19th, December 3rd, December 18th, January 2nd, January...

H. Mazija, I. Ciglar Grozdanić, K. Matanović, M. Vilić, P. Kraljević, S. Miljanić, Ž. Gottstein,

Background: The specific antibody response against Newcastle disease virus (NDV) in the blood serum of chickens hatched from eggs exposed to low dose gamma-radiation was studied. Materials and methods: Two groups of eggs of commercial meat chicken lines were irradiated with the dose of 0.30 Gy 60Co gamma-rays before incubation and on the 19th day of incubation, respectively. The same num...

2014
Krishna R. Veeramah Ryan N. Gutenkunst August E. Woerner Joseph C. Watkins Michael F. Hammer Sohini Ramachandran

Partially recessive variants under positive selection are expected to go to fixation more quickly on the X chromosome as a result of hemizygosity, an effect known as faster-X. Conversely, purifying selection is expected to reduce substitution rates more effectively on the X chromosome. Previous work in humans contrasted divergence on the autosomes and X chromosome, with results tending to suppo...

1999

1. The purpose of the in vitro chromosome aberration test is to identify agents that cause structural chromosome aberrations in cultured mammalian cells (1)(2)(3). Structural aberrations may be of two types, chromosome or chromatid. With the majority of chemical mutagens, induced aberrations are of the chromatid type, but chromosome-type aberrations also occur. An increase in polyploidy may ind...

Journal: :asia pacific journal of medical toxicology 0
reza afshari 1 environmental health services, bc centre for disease control, vancouver, canada.2 occupational and environmental division. school of population and public health, university of british columbia, vancouver, canada.

0

Journal: :American journal of human genetics 2007
Peter M Visscher Stuart Macgregor Beben Benyamin Gu Zhu Scott Gordon Sarah Medland William G Hill Jouke-Jan Hottenga Gonneke Willemsen Dorret I Boomsma Yao-Zhong Liu Hong-Wen Deng Grant W Montgomery Nicholas G Martin

Height has been used for more than a century as a model by which to understand quantitative genetic variation in humans. We report that the entire genome appears to contribute to its additive genetic variance. We used genotypes and phenotypes of 11,214 sibling pairs from three countries to partition additive genetic variance across the genome. Using genome scans to estimate the proportion of th...

2010
Jonathan M. J. Derry Hua Zhong Cliona Molony Doug MacNeil Debraj Guhathakurta Bin Zhang John Mudgett Kersten Small Lahcen El Fertak Alain Guimond Mohammed Selloum Wenqing Zhao Marie France Champy Laurent Monassier Tom Vogt Doris Cully Andrew Kasarskis Eric E. Schadt

To identify the genes and pathways that underlie cardiovascular and metabolic phenotypes we performed an integrated analysis of a mouse C57BL/6JxA/J F2 (B6AF2) cross by relating genome-wide gene expression data from adipose, kidney, and liver tissues to physiological endpoints measured in the population. We have identified a large number of trait QTLs including loci driving variation in cardiac...

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