BACKGROUND Hallux valgus (HV) is a very common deformity of the first metatarsophalangeal joint that often requires surgical correction. However, the association between structural HV deformity and related foot pain and disability is unclear. Furthermore, no previous studies have investigated concerns about appearance and difficulty with footwear in a population with HV not seeking surgical cor...

Background Hallux valgus (HV) is a progressive foot deformity involving lateral deviation of the hallux, and a common indication for forefoot surgery. However, the degree of foot pain experienced by individuals with HV is unclear. Recent evidence suggests an association between HV and foot pain; whereas, other studies have found no association. Furthermore, it is unknown whether more severe HV ...

BACKGROUND Identifying the potential for drug-induced kidney injury is essential for the successful research and development of new drugs. Newer and more sensitive preclinical drug-induced kidney injury biomarkers are now qualified for use in rat toxicology studies, but biomarkers for clinical studies are still undergoing qualification. The current studies investigated biomarkers in healthy vol...

For each vertex v in a graph G, let there be associated a subgraph Hv of G. The vertex v is said to dominate Hv as well as dominate each vertex and edge of Hv. A set S of vertices of G is called a full dominating set if every vertex of G is dominated by some vertex of S, as is every edge of G. The minimum cardinality of a full dominating set of G is its full domination number γFH(G). A full dom...

Some general Finsler connections are defined. Emphasis is being made on the Cartan tensor and its derivatives. Vanishing of the hv-curvature tensors of these connections characterizes Landsbergian, Berwaldian as well as Riemannian structures. This view point makes it possible to give a smart representation of connection theory in Finsler geometry and yields to a classification of Finsler connec...

in this paper, the accumulative channel-die compression bounding (accb) method is investigated as a new method of severe plastic deformation to produce nano-crystalline bulk metals on the basis of pressing in a channel mold. aluminum as one of the most usable metal in industry is processed using this method. analyzing the processed samples show that after four passes of accb method, the ultimat...

Spleen cells primed by Prospect Hill (PH) or Puumala (Pu) virus could cross-react with Hantaan virus (HV) 76-118 strain-infected target cells after in vitro stimulation with HV-infected cells, although anti-PH or anti-Pu immune serum showed no cross-reactive neutralizing (NT) activity to HV without complement. These results and our previous findings with cross-reactive cytotoxic T lymphocytes (...

Gene electrotransfer is gaining momentum as an efficient methodology for nonviral gene transfer. In skeletal muscle, data suggest that electric pulses play two roles: structurally permeabilizing the muscle fibers and electrophoretically supporting the migration of DNA toward or across the permeabilized membrane. To investigate this further, combinations of permeabilizing short high-voltage puls...

The extracellular matrix (ECM) environment plays a critical role in organism development and disease. Surface sensitive microscopy techniques for studying the structural and chemical properties of ECMs are often performed in high vacuum (HV) environments. In this report, we examine the affect HV conditions have on the bioactivity and mechanical properties of type I collagen fibrillar matrices. ...

We displayed backward/forward motion on a computer monitor in the ground plane. Subjects looked at the center of a moving pattern and eye movements of both eyes were recorded with a search coil system. Involuntary nystagmus including vertical version (VV) and horizontal vergence (HV) was recorded. Dynamics of the nystagmus showed that the slow and quick phase of VV and HV were always associated...