The term "hyaline degeneration ", first employed by von Recklinghausen (1883), denotes a physical state rather than a chemical composition. " Hyalin" includes a heterogenous group of substances which share the properties of being translucent, refractile, and structureless (Gk, hyalos-glass). They stain readily with acid dyes, are resistant to strong acids and alkalis, and are all of a protein n...

of lungs obtained at necropsy from 44 children at or above the 50th centile dying from non-pulmonary causes were described. In the present paper some results from the analysis of 92 further pressure-volume curves are described. These were compared with the theoretically normal values according to total body length, by dividing the observed value by the theoretically normal one. This was done fo...

Hyaline fibromatosis syndrome is the current name for clinical manifestations of diseases previously known as "infantile systemic hyalinosis" and "juvenile hyaline fibromatosis". The authors report representative clinical cases of each one of the above subtypes with emphasis on cutaneous manifestations and difficulties for early diagnosis in this syndrome, essentially of multidisciplinary appro...

BACKGROUND Cytologic diagnosis of pulmonary adenoid cystic carcinoma (AdCC) is frequently challenging and differential diagnosis with small cell carcinoma is often difficult. METHODS Eleven cytologically diagnosed cases of pulmonary AdCC were collected and reviewed according to fifteen cytomorphologic characteristics: small cell size, cellular uniformity, coarse chromatin, hyperchromasia, dis...

Despite numerous attempts to develop and evalute specsc methods for the histochemical demonstration of mucopolysaccharides, definitive information is not readily available. Thls is in spite of the notable contributions of Hale ('46); Steedman ('50); Gomori ('50); Kramer and Windrum ('54); Mowry ('56, '58); Spicer ('60); Belanger and Migicovsky ('61) and Goldstein ('62) to mention only a few. Wi...

A 72-year-old woman with CIDP was treated with IVIG. During the second day of treatment, the patient noticed an increase in abdominal girth and a decrease in urine output, without other symptoms. Laboratory findings included serum creatinine of 4.6mg/dl (407mmol/l) and blood urea nitrogen of 65mg/dl (23.2mmol/l). Urinalysis showed 2þ protein and many hyaline casts. A renal biopsy was done to de...

Lipoid proteinosis (LP) is an extremely rare autosomal recessive genodermatosis, characterized by persistent hoarseness and classical skin lesions. Amorphous hyaline depositions may affect any organ, but mainly the face extremities. These cause limitations in tongue movement, hence, difficulty speaking. Biopsies of lesions usually show massive deposits homogeneous, acidic, hyaline-like material...

Mallory's (;alcoholic') hyaline has been found in hepatocytes in 18 of 70 patients with primary biliary cirrhosis. These inclusions have previously been noted in only three cases of primary biliary cirrhosis. Current views on the nature of Mallory's hyaline are briefly discussed.

Infantile systemic hyalinosis is a rare disorder characterized by widespread deposition of hyaline. They usually present with skin lesions, joint contractures, and intractable diarrhea. We report a 2 year 4 month old boy with growth retardation, typical facial appearance, gingival enlargement, generalized stiff skin, joint contractures, and intermittent diarrhea. Skin biopsy revealed depositio...

AIMS We retrospectively analyzed clinicopathologic features of 8 cases of hepatitis B virus-associated glomerulonephritis with hyaline thrombi, to confirm the diagnosis of cryoglobulinemic glomerulonephritis (CRYGN) associated with HBV infection. METHODS Retrospective analysis was carried out with demographic information, clinical manifestations, laboratory parameters, pathological and progno...