Markov Decision Processes are a powerful framework for planning under uncertainty, but current algorithms have difficulties scaling to large problems. We present a novel probabilistic planner based on the notion of hybridizing two algorithms. In particular, we hybridize GPT, an exact MDP solver, with MBP, a planner that plans using a qualitative (nondeterministic) model of uncertainty. Whereas ...

Immunoglobulin kappa-chain mRNA was hybridized with DNA in order to assess the kappa-gene frequency. Kappa-mRNA was purified from membrane-bound ribosomes of mouse myeloma MOPC-41 by poly (U) chromatography and isolation of a 13S RNA by successive sucrose density gradient centrifugations. The RNA coded for kappa-chain precursor molecules in cell-free protein synthesis and essentially no other p...

The shortening of the design cycle and the increase of the performance are nowadays the main challenges in aerodynamic design. The use of evolutionary algorithms (EAs) seems to be appropriate in a preliminary phase, due to their ability to broadly explore the design space and obtain global optima. Evolutionary algorithms have been hybridized with metamodels (or surrogate models) in several work...

The effect of enrichment bias on the diversity of 2,4-dichlorophenoxyacetate (2,4-D)-degrading (2,4-D(sup+)) bacteria recovered from soil was evaluated by comparing the diversity of isolates obtained by direct plating to the diversity of isolates obtained from 85 liquid batch cultures. By the two methods, a total of 159 isolates were purified from 1 g of soil and divided into populations based ...

AIM To design a novel method to rapidly detect the quantitative alteration of mtRNA in patients with tumors. METHODS Oligo 6.22 and Primer Premier 5.0 bio-soft were used to design 15 pairs of primers of mtRNA cDNA probes in light of the functional and structural property of mtDNA, and then RT-PCR amplification was used to produce 15 probes of mtRNA from one normal gastric mucosal tissue. Tota...

164 Abstract We have developed an allotyping assay for detection of four HLA DRB1*01 group alleles based on polymerase chain reaction and solution hybridization in a microtiter plate. Using group specific primers a region within exon 2 of HLA DRB1 gene was amplified by PCR. Labeling of PCR product was achieved by adding small amount of Dig-dUTP in place of dTTP. Labeled PCR product was hybridiz...

Anaplasmosis can be diagnosed either by immunological techniques or by direct microscopic examination of blood smears. Both methods are time-consuming and labour intensive. The use of DNA probes in an hybridization assay may simplify the diagnosis of anaplasmosis in cattle and sheep. A genomic DNA library of Anaplasma centrale was constructed in an expression vector and screened to detect clone...

Dimensionality reduction of a feature set is a common preprocessing step used for pattern recognition, classification applications and in compression schemes. Rough Set Theory is one of the popular methods used, and can be shown to be optimal using different optimality criteria. This paper proposes a novel method for dimensionality reduction of a feature set by choosing a subset of the original...

In this paper we introduce hybridized fireworks algorithm for global optimization problems. We replaced Gaussian search method from the original fireworks algorithm with the search equation adopted from the firefly algorithm. To test our approach, we implemented six standard bound-constrained benchmarks and performed comparative analysis with the basic fireworks algorithm, as well as with two o...