نتایج جستجو برای: hydantoin derivatives
تعداد نتایج: 105363 فیلتر نتایج به سال:
Imidazolidine derivatives, or hydantoins, are synthetic compounds with different therapeutic applications. Many imidazolidine derivatives have psychopharmacological properties, such as phenytoin, famous for its anticonvulsant efficacy, but also effective in the treatment of neuropathic pain. The hydantoin, 3-phenyl-5-(4-ethylphenyl)-imidazolidine-2,4-dione (IM-3), synthesized from the amino aci...
Methoxymethylation of a variety of alcohols was performed using formaldehyde dimethyl acetal in the presence of 1,3-dichloro-5,5-dimethyl hydantoin [DCDMH] and Poly N,N′-dibromo-N-ethyl naphthyl-2,7-disulfonamide [PBNS] as catalysts at room temperature and under solvent-free conditions. Our experiments show that primary and secondary alcohols can be smoothly converted into the corresponding MOM...
I ABSTRACT Phenobarbital is a drug of barbiturates class that it’s Anticonvulsant and sedative effects has been caused it’s widely. Usage in nervous system diseases espicially epilepsy. The epileptic pregnant women who taking this dr...
Three 5-nitrofuran derivatives showed carcinogenic activity when fed to female Holtzman rats at levels of 0.1 to 0.3% in a commercial diet for up to 44.5 weeks, while 2 other 5-nitrofuran derivatives and 5,5-diphenylhydantoin were inactive. Formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl]hydrazide induced benign and malignant tumors of the mammary glands, adenomas or adenocarcinomas of the kidne...
The title compound is a hydantoin derivative that has been synthesized through three-component reaction of ethyl pyruvate, p-anisidine and phenyl isocyanate. This paper provides comprehensive spectral dataset for the compound, including 1H 13C{1H} NMR, IR, HRMS, X-ray crystallography analyses. A tentative mechanism comprising two complementary pathways provided based on additional experiments w...
To evaluate the efficiency of modified epoxy resins using bisphenol-A, hydantoin & cyanuric acid & to investigate the structural change due to the presence of Nitrogen atoms in polymeric chain for improved insulating properties, weatherability etc. The samples of epoxy resin bisphenol-A, hydantoin and Cyanuric acid based was taken for X-ray diffraction analysis. The diffraction patterns were Fo...
We have been exploring the mechanism of action of 5-(3,4-dichlorophenyl) methylhydantoin (hydantoin), an antiviral drug that inhibits the replication of poliovirus in culture. By varying the time of drug addition to infected cells, we found that the drug acts at a stage which is late in the replication cycle and subsequent to the step inhibited by guanidine. Furthermore, we detected normal leve...
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