Renal (peritubular) tissue hypoxia is a well-known physiological trigger for erythropoietin (EPO) production. We investigated the effect of rebound relative hypoxia after hyperoxia obtained under normo- and hyperbaric oxygen breathing conditions. A group of 16 healthy volunteers were investigated before and after a period of breathing 100% normobaric oxygen for 2 h and a period of breathing 100...

Beside conventional therapy, the management of necrotizing cellulitis and fasciitis is based on non-pharmacological treatments. Hyperbaric oxygen therapy and dressings are the most frequently used techniques. The usefulness of hyperbaric oxygen therapy is clearly demonstrated in experimental studies while the efficacy of this technique is poorly assessed in clinical practice. The French consens...

OBJECTIVE To report a case of Aspergillus flavus malignant otitis externa, successfully treated with antifungal agents, surgical debridement, and hyperbaric oxygen treatment. PATIENT The case was a 77-year-old man with non-insulin dependent diabetes mellitus, who presented with otalgia and purulent otorrhea. Intervention was with surgical debridement, antifungal agents, and hyperbaric oxygen ...

The aim of the study was to assess the influence of hyperbaric oxygen on regeneration processes which take place in the inner ear (basilar papilla - BP) of chicken after exposure to wide-band noise at the level 120 dB for 48 hours. We found, that hyperbaric oxygen applied once a day after exposure to the noise restricted he extensiveness and decreased the dynamics of hair cells injury. Quantati...

Five-week-old normotensive Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) were subjected to hyperbaric oxygenation with an enhanced atmospheric pressure (950 mmHg) and an increased oxygen concentration (36%) for 6 h per day. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were monitored for 8 weeks of hyperbaric oxygenation period. After 8 weeks of hyperbaric...

OBJECTIVE Review the historical development and physiologic principles of hyperbaric oxygen therapy (HBOT) based on human and veterinary experimental literature and current equipment in use. DATA SOURCES Review of basic physiologic concepts. Data from human and veterinary journals were reviewed through Pubmed and Veterinary Information Network database searches as well as reference searches o...

CO is likely to be the most common cause of poisoning worldwide and often results in persistent neuropathologic and cognitive sequelae. While the displacement of oxygen from hemoglobin by CO has overshadowed the myriad mechanisms by which CO causes injury, mere oxygen displacement has endured as the etiology of CO poisonings and perpetuated a cascade of misdiagnosis, misunderstandings and confu...

OBJECTIVE Our aim was to investigate the effects of growth hormone (GH), hyperbaric oxygen and combined therapy on normal and ischemic colonic anastomoses in rats. METHODS Eighty male Wistar rats were divided into eight groups (n = 10). In the first four groups, non-ischemic colonic anastomosis was performed, whereas in the remaining four groups, ischemic colonic anastomosis was performed. In...