Celiac disease (CD) or gluten sensitive enteropathy is relatively common in western populations with prevalence around 1%. With the recent availability of sensitive and specific serological testing, many patients who are either asymptomatic or have subtle symptoms can be shown to have CD. Patients with CD have modest increases in risks of malignancy and mortality compared to controls. The morta...

BACKGROUND The main aim of this prospective study was to evaluate the efficacy of drug-eluting beads with irinotecan (DEBIRI) for liver metastases from colorectal cancer. Secondary aims were to evaluate survival and toxicity. METHODS Twenty-five patients with metastases in <50% of the liver and without extrahepatic involvement were enrolled. Treatment response assessment was performed by mult...

E suggests a linkage between different environmental agents and the development of celiac disease—an immune-mediated disorder—in those with a specific genetic predisposition (HLADQ2, HLA-DQ8) who exposed to gluten—a major storage protein in wheat and other grains. Infections, particularly viral agents, have been hypothesized to induce or exacerbate immune-mediated disorders, possibly through a ...

Few studies have been performed on the prevalence of Torque Teno Virus (TTV) infection in liver transplant (LT) recipients. The aim of this study was to assess the prevalence, viremia and genogroup pattern of TTV among LT patients and to ascertain whether TTV causes liver damage in liver transplanted patients with biochemical and histological changes of unknown origin. Twenty-five patients were...

At present the treatment of chronic hepatitis C virus infection is based on the combination of pegylated interferon (PEG-INF) and rivabirin (RBV) and basically attempts to eradicate the viral infection (sustained viral response). The pattern depends above all on the viral genotype, hence, patients with genotype 1, 4 and 5 require 48 weeks of treatment and high doses of RBV, while those with gen...

We report the case of a two-year-five-month-old child who underwent screening for celiac disease due to strong familiarity. During the first observation body weight and height were at 25th and 50th centile for gender and age. Physical examination did not reveal any sign of disease. Blood tests showed increased transaminases levels and antibodies research showed: tTG IgA: 100 UI/ml, tTG IgG: 36,...

Objective: The aim of the study was to determine the association between fatty liver and obesity in patients presenting to King Abdulaziz University Hospital. Methods: This is a retrospective study reviewing medical records of all obese patients having a fatty liver over a one-year period between April 2003 and April 2004. The data collected included age, gender, nationality, BMI, serum level o...

BACKGROUND Persistently raised transaminase levels often prompt the clinician to investigate for liver pathology. Previously, some of our patients with Duchenne's muscular dystrophy have had investigations to look for liver disorders when the alanine transaminases (ALTs) were found incidentally to be high. AIM The objective of the study was to ascertain the levels of the transaminases in pati...

Introduction: Post-marketing identification and report of unknown adverse drug reactions (ADRs) are crucial for patient safety. However, complete information on ADRs seldom is available at the time spontaneous ADR reports this can hamper their contribution to pharmacovigilance system. Methods: In order characterize seriousness outcome follow-up, analyze generate regulatory actions, a retrospect...

Abstract Fulminant myocarditis (MF) is an acute onset, rapidly progressive and potentially fatal inflammatory cardiomyopathy which could manifests with cardiogenic shock incessant arrhythmias. There often a need for aminic or mechanical support to the circulation in phase, waiting obtain histological diagnosis as quickly possible establish specific therapy. Mortality phases high, worse prognosi...