Infantile hypertrophic pyloric stenosis (IHPS) is one of the most common gastrointestinal disorders requiring abdominal surgery in infancy. Whilst the operation is relatively routine and complications are low in developed countries, in resource poor settings, the condition can be fatal due to lack of paediatric surgeons and neonatal aneasthetists in most hospitals. However, current WHO guidance...

Infantile hypertrophic pyloric stenosis (IHPS) is a common cause of gastric outlet obstruction in infant. The prevalence of IHPS ranges from 1.5 to 4.0 in 1000 live birth1. But the incidence of IHPS has been increasing approximately from 1.5 to 4.0 in 1000 live birth to 1:1502. Though pyloric atresia is a very uncommon cause of gastric outlet obstruction in infant but atresia in this region occ...

The serum immunoreactive gastrin (IRG) level in infants with confirmed idiopathic hypertrophic pyloric stenosis (IHPS) has been determined and compared to that found in vomiting infants without IHPS, in normal infants, and in normal adults. The mean serum IRG level of normal infants (103 +/- 9 pg/ml (mean +/- SEM) exceeded that of normal adults (28 +/- 5 pg/ml). The preoperative mean serum IRG ...