Idiopathic pulmonary hemosiderosis (IPH) is a rare, life-threatening disease of uncertain etiology, characterized by recurrent intra-alveolar hemorrhages and usually afflicting young adults or children(l). Symptoms of lung hemorrhage are often few and atypical(2). Consequently, the condition may go unrecognized for a few years or months, presenting as recurrent iron deficiency anemia with no ac...

Recent clinical trials evaluating gallium nitrate as a chemotherapeutic agent have reported the development of microcytic hypochromic anemia in patients treated with this agent. Because gallium is known to bind avidly to transferrin, we examined the effect of transferrin-gallium (Tf-Ga) on hemoglobin production by Friend erythroleukemia cells in vitro. Cellular hemoglobin production, as assesse...

Iron-deficiency anemia (IAD) in children is the most common among other types of anemia. It is commonly presented in children aged between 6—36 months than at other age groups, according to a report. Pediatric iron-deficiency anemia might involve multiple etiological factors including low birth weight, nutritional deficiency, and gastrointestinal blood loss. Diagnosis is made on the basis of de...

BACKGROUND Anemia is a common complication of chronic kidney disease. We investigated the prevalence, characteristics and management of anemia in patients on chronic hemodialysis and assessed the response to blood-transfusion based management in Cameroon. METHODS This was a cohort study of five months' duration (August-December 2008) conducted at the Yaoundé General Hospital's hemodialysis ce...

This paper describes a 7-year-old girl with trichodysplasia, normal teeth, onychogryposis, hypohidrosis, psychomotor and growth retardation, dry and warm skin with follicular hyperkeratosis, pigmentary disturbances (hyper- and hypochromic spots), bilateral nuclear cataract, dermatoglyphic anomalies, and other signs. This condition is considered a new form of ectodermal dysplasia.

Ectopic cilia are rare in humans. We report a 6-year-old girl with typical characteristics of ectopic cilia as described in the rare cases reported in the literature, in association with cutaneous lesions that appeared to be hypochromic nevi. This framework could be a different clinical presentation of ectopic cilia.

A patient with Von Recklinghausen's disease who developed a retroperitoneal neurofibrosarcoma is described. The presenting clinical picture was one of hypochromic anaemia with a large mass palpable in the left hypochondrium. At operation the tumour was found to be invading the small intestine with resultant blood loss. The patient had presented 21 years before with unexplained severe iron defic...

Background To study the seroprevalence of hepatitis C virus in multi-transfused children with b-thalassemia and compared with non transfused children and healthy controls. b-thalassemic children fail to thrive, with growth and developmental retardation and suffer microcytic hypochromic anemia. Since regular blood transfusions are given to maintain haemoglobin at a safe level, these children are...