The hypoglycemic effects of water and butanolic extracts prepared from the bark of Acosmium panamense (Fabaceae) were studied in diabetic rats (streptozotocin (STZ)-induced). Oral application of water extracts at doses of 20 and 200 mg/kg and of butanol extracts at doses of 20 and 100 mg/kg significantly lowered the plasma glucose levels in diabetic rats within 3 h. Glibenclamide was used as re...

the hypoglycemic effect of the ethanolic extract of Momordica charantia (cucurbitaceae) was investigated in both normal and streptozotocin - induced diabetic mice. The ethanolic extract of Unriped fruits of M. charantia (800mg/kg) reduced the blood glucose of normal mice from 172 ±3 to 136 ± 5 mg/100ml 4 hours after intrapertitoneal administration (P<0.001), and also significantly lowered the b...

This present study was conducted to evaluate the hypoglycemic effect of aqueous extract of stem and bark of Coscinium fensestratum colebr in normal rats. Total 18 rats were selected and divided into the three groups each of 6 rats. G-I given 1% gum acacia, G-II given aqueous extract of C.F stem (500 mg/kg) and G-III treated with aqueous extract of C.F bark (500 mg/kg). Test drugs were given sin...

Abstract Introduction: Since its discovery in 1921, insulin has served as the mainstay of treatment for patients with both type 1 and insulin-dependent 2 diabetes mellitus (T2DM). Insulin is available long short acting formulations. Glargine, a long-acting insulin, an onset action one to two hours length duration 24 hours. Although generally well tolerated, when taken overdose, can lead severe ...