The present study was undertaken to evaluate the efficacy of freeze dried extract of Clerodendron glandulosum Coleb., Verbenaceae, leaves (FECG) on alteration in lipid and cholesterol metabolism in high fat diet fed hyperlipidemic rats. Plasma and hepatic lipid profiles, lipid and cholesterol metabolizing enzymes in target tissues and fecal total lipids and bile acid contents were evaluated in ...

A series of substituted 2-phenacyl-3-phenyl-1H-pyrrole-4-carboxylates were prepared from substituted acetophenones in 6 steps. The final condensations between a chloroenal and an aminoketone were carried out under neutral conditions in parallel to yield the series listed below. Selected pyrrole derivatives proved to be potent hypolipidemic agents lowering serum triglyceride concentrations in CF...

The present study was undertaken to evaluate antioxidant and hypolipidemic activity of Vedic guard, a polyherbal formulation comprising of Terminalia arjuna, Withania sominefera, Bacopa monnierii, Tinosporia cardifolia, Commiphora mukul and many other plant extracts, all of which are classifieds in Ayurveda as Rasaayanas which are reported to promote antioxidant and hypolipidemic activity. Anti...

Spirulina is free-floating filamentous microalgae growing in alkaline water bodies. With its high nutritional value, Spirulina has been consumed as food for centuries in Central Africa. It is now widely used as nutraceutical food supplement worldwide. Recently, great attention and extensive studies have been devoted to evaluate its therapeutic benefits on an array of diseased conditions includi...

BACKGROUND Antidesma bunius (L.) Spreng has been reported to possess various beneficial medicinal properties. Scientific information about this plant is limited. This study was therefore, designed to determine hypoglycaemic and hypolipidemic effects of ethanol seed extract from A. bunius (ABSE). Antioxidant activity and also acute toxicity were conducted. METHODOLOGY The hypoglycaemic and hyp...

agent technology is an emerging and promising research area in software technology, which increasingly contributes to the development of value-added information systems for large healthcare organizations due to its capability to automatically modify themselves in response to changes in their operating environment. multi agent system (mas) approach is the construction of a complex system as a se...

Aged garlic extract (AGE) is one of the unique preparations standardized with 100% bioavailable active ingredients found in the bloodstream. The current research was aimed at exploring the role of AGE and its chief active constituent, s-allyl cysteine (SAC) as antioxidant and hypolipidemic agent in rats. At the end of treatment of AGE and SAC, separated serum and freshly prepared liver tissue h...

Nephrotic syndrome (NS) is still a therapeutic challenge. To date there is no ideal treatment. Evidence suggest that multidrug therapy has more effect than monotherapy in amelioration of renal injury. Salvianolic acid A (SAA) is the major active component of Salviae Miltiorrhizae Bunge. Previous studies have demonstrated that SAA is a multi-target agent and has various pharmacological activitie...

Insect-derived chitin and chitosan have gained interest as alternative sources to that derived from crustaceans; however, little information is available on the house cricket (Acheta domesticus) tropical banded (Gryllodes sigillatus), two species commonly reared in United States for human consumption. In this study, was successfully isolated purified these species; using FTIR, chitins were foun...

Gugulipid is an ethyl acetate extract of guggul resin, obtained from Commiphora wightii (Fam.: Burseraceae) and is official in Indian Pharmacopoeia (1). The active constituent of gugulipid is guggulsterone (4,17(20)-pregnadiene3,16-dione) (2), which is present in a concentration of 4.0ñ6.0%.The guggulsterone is present in guggulipid in the form of stereoisomers E-guggulsterone and Z-guggulstero...