Introduction Magnesium is an N-methyl-D-aspartate receptor blocker and it’s known to have analgesic effect [1,2]. Hypomagnesaemia is often seen in major surgery and it is associated with higher morbidity, mortality, organ dysfunction, systemic inflammatory response syndrome and pulmonary hypertension [2,4]. It’s shown that intra-operative use of magnesium sulfate reduced per-operative analgesic...

The kidney plays a key role in the maintenance of normal magnesium balance. The distal tubule of the kidney, namely the thick ascending limb of the loop of Henle and the distal convoluted tubule, is crucial for the regulation of serum magnesium levels and body magnesium content. The identification of molecular defects related to rare inherited magnesium losing disorders has contributed greatly ...