BACKGROUND/AIMS Instrumental activities of daily living (IADL) impairment in Alzheimer's disease has been associated with global amyloid deposition in postmortem studies. We sought to determine whether IADL impairment is associated with increased cortical Pittsburgh Compound B (PiB) retention. METHODS Fifty-five subjects (19 normal older controls, NC, and 36 with mild cognitive impairment, MC...

BACKGROUND/AIMS We investigated quantitative/qualitative changes of instrumental activities of daily living (IADL) in people with a Clinical Dementia Rating (CDR) of 0.5. METHODS IADLs were evaluated in older residents: CDR of 0 (healthy) and CDR 0.5 (questionable/very mild dementia). The subjects with CDR 0.5 were divided into 2 types: the very mild Alzheimer's disease (vmAD) type and the ot...

PURPOSE Assess the validity of our previously published multidimensional concept of Successful Aging that integrates physiological, psychological, and sociological domains of health. DESIGN Three distinctly different populations were used to assess the discriminant and predictive validity. METHODS Data included 1438 women age 65 and older who participated in the Women's Health and Aging Stu...

The present study examined the effects of cognitive impairment and functional limitation on depressive symptoms among older Korean American immigrants. The sample was drawn from a cross-sectional survey of 210 older Korean immigrants (aged 65 years or older) in Los Angeles County. Based on robust hierarchical regression, the study found that cognitive ability and functional status were signific...

Results: It was found that 80.6% of the elderly were independent in the ADL and 79.8% were independent in the IADL. On the whole, they show a reasonable quality of life. The study of the correlation between the results of the perception of the quality of life and the levels of independence in the ADL and the IADL revealed that the more independent elderly people tend to perceive a better qualit...

objectives: the purpose of this study was to determine the of physical functioning level and prevalence of chronic illness among elderlypeople in west region of tehran. methods & materials: this study was a descriptive and cross-sectional study. a multi-stage sampling was used and 410 community residents who were over 60 years old were selected from west region of tehran.descriptive statistics,...

OBJECTIVE To investigate whether there is a difference in balance function between older persons with and without diabetes mellitus (DM), and to identify whether mediating factors, such as diabetic complications, Instrumental Activities of Daily Living (IADL) score, Mini-Mental State Examination (MMSE) score, as well as hemoglobin A1c (HbA1c), fasting plasma glucose (FPG), serum total cholester...

Objectives. To investigate the link between neurocognitive measures and various aspects of daily living (ADL and IADL) in women and men with mild Alzheimer's disease (AD). Methods. Participants were 202 AD patients (91 male, 111 female) with CDR global scores of ≤1. ADLs and IADLs ratings were obtained from caregivers. Cognitive domains were assessed with neuropsychological testing. Results. Me...

Objective: The present study compared cognitive function and the ability to perform daily activities in subjects with very mild dementia, classified by presence or absence of sleep disturbances depression. Methods: A total 1,188 psychiatric outpatients (457 males 731 females, mean age=74.65±5.83 years) were recruited. Sleep measured Korean version Neuropsychiatric Inventory depression was Geria...