A problem-orientated case record was used for the investigation and management of neonatal jaundice. Investigation of babies requiring phototherapy rarely showed any abnormality but we consider that such routine investigations are worth retaining. There were problems in the interpretation of moderately low plasma concentrations of thyroxine in small, preterm babies. There was biochemical eviden...

OBJECTIVE To determine the pattern of liver diseases diagnosed in children at Ga-Rankuwa Hospital Histopathology Laboratory. DESIGN A retrospective study. SETTING Ga-Rankuwa Histopathology Laboratory. SUBJECTS Seventy two patients who underwent a liver biopsy during the study period. METHODS Laboratory records were reviewed and all liver biopsies were extracted. All slides were reviewed...

Background: The spectrum of hepatobiliary disorders in children is different from those of adults and include a variety of acute and chronic disorders and these variations are attributable to different factors and they vary with geographical area.Therefore, there is need of such study to find out the spectrum of hepatobiliary diseases in different areas. Aim:To find out the existing pattern of ...

AIMS To investigate the distribution of alpha and pi class glutathione S-transferases (GST) in normal fetal, neonatal, and adult liver; and to examine changes in GST expression in neonatal liver disease. METHODS alpha and pi class GST were immunolocalised in sections of formalin fixed liver tissue obtained from human fetuses (n = 21), neonates (n = 8), young children (n = 9) and adults (n = 1...

Idiopathic pulmonary fibrosis is an increasingly recognized problem with a poor prognosis. The aetiology remains unclear. However, many patients date the onset of their disease to a recent viral infection, implying that viruses may have a potential role in disease progression. A number of studies have suggested an association between idiopathic pulmonary fibrosis and viruses including adenoviru...

Neonatal scrotal hematoma is a rare genitourinary emergency. Some cases have underlining aetiologic factors such as testicular torsion, adrenal hemorrhage, or birth trauma, and others are idiopathic. Previously, immediate scrotal exploration was considered imperative for diagnosis and treatment. With good imaging techniques, some patients are managed nonoperatively. We report a case of idiopath...