Infective endocarditis (IE) is a life-threatening disease with substantial morbidity and mortality which affects individuals with underlying structural cardiac defects who develop bacteraemia, often as a result of dental, gastrointestinal, genitourinary, respiratory or cardiac invasive/surgical procedures. Prompt recognition of the clinical diagnosis by a wide variety of medical personnel, earl...

High circulating concentrations of homocysteine (ie, hyperhomocysteinemia [Hhcy]) impair the vascular function of peripheral conduit arteries and arterioles perfusing splanchnic and skeletal muscle regions. The effects of HHcy on coronary resistance vessel function and other indexes of vascular function, ie, arterial permeability and stiffening, are unclear. We tested the hypotheses that HHcy i...

le mouvement transversal de la locomotive ou des wagons , appele ie lacet, provient de deux causes principales: -la conicite des bandages -les irregularites de la voie dans ie plan horizontal. on se propose ici d'etudier la premiere cause , ce qui nous conduit a une equation differentielle non lineaire du deuxieme ordre. • l'equation en question est etudiee dans plusieurs cas difftten...

We design and release BONIE, the first open numerical relation extractor, for extracting Open IE tuples where one of the arguments is a number or a quantity-unit phrase. BONIE uses bootstrapping to learn the specific dependency patterns that express numerical relations in a sentence. BONIE’s novelty lies in task-specific customizations, such as inferring implicit relations, which are clear due ...

HIV-1 infection increases the risk and severity of malaria by poorly defined mechanisms. We investigated the effect of HIV-1(Ba-L) infection of monocyte-derived macrophages (MDM) on phagocytosis of opsonised P. falciparum infected erythrocytes (IE) and subsequent proinflammatory cytokine secretion. Compared to mock-infected MDM, HIV-1 infection significantly inhibited phagocytosis of IE (median...

Nocardia is a rare opportunistic agent, which may affect immunocompromised individuals causing lung infections and exceptionally infective endocarditis (IE). There are few reports of IE caused by Nocardia sp., usually involving biological prostheses but rarely in natural valves. Its accurate microbiological identification may be hampered by the similarity with Rhodococcus equi and Corynebacteri...

JEM © The Rockefeller University Press $30.00 Vol. 205, No. 4, April 14, 2008 967-979 www.jem.org/cgi/doi/ 967 10.1084/jem.20072051 Rheumatoid arthritis (RA) is a chronic disease aff ecting the peripheral joints in which abnormalities in the synovium precipitate a destructive process that often leads to cartilage and bone erosion. The autoimmune nature of this disease has been defi ned, in part...

Previous studies have typically found that individuals with schizophrenia (SZ) report levels of emotional experience that are similar to controls (CN) when asked to view a single evocative stimulus and make an absolute judgment of stimulus "value." However, value is rarely assigned in absolute terms in real-life situations, where one alternative or experience is often evaluated alongside others...

OBJECTIVES Infective endocarditis (IE) remains a serious disease with substantial mortality. In this study we investigated the incidence of IE, as well as its associated short and long term mortality rates. METHODS The IE cases were identified in the Swedish national inpatient register using ICD-10 codes, and then linked to the population register in order to identify deaths in the cohort. Cr...