The structure of the ribosomal 5 S RNA was examined using Fe(II)-EDTA, a solvent-based reagent that cleaves the phosphodiester backbone of both double- and single-stranded RNA but is restricted by the three-dimensional structure. In the yeast 5 S RNA, cleavages were significantly restricted in six specific regions of the molecule; restrictions in only two of these regions were clearly dependent...

one of the methods of preventing crimes is ‘situational prevention’ that is to design environment, change physical conditions and with controlling of environment and crime opportunities decreases the rate of crime in the society. some of these ways concentrates on environmental changes, control of criminals and supporting weak victims and taking care of crime targets. since development of civil...

todays, decision makers in the organization need toconstantly monitor changes in the environment and organization andmake necessary changes. therefore knowledge about the environmentand organization is necessary in decision making. knowledgemanagement is a key factor for competitive business environment andorganizations are investing heavily in creating centralized knowledgerepositories to impr...

When designing an IT platform aimed at supporting industrial Virtual Enterprises (VEs), certain issues related to information management requirements become especially challenging, such as the physical distribution of data, the enterprise autonomy and privacy enforcement, access rights to shared information, and data visibility levels, among others. In the ESPRIT project PRODNET II, a federated...

The potential to foster successfully starts with developing and supporting competency in 12 domains: providing a safe and secure environment, providing a nurturing environment, promoting educational attainment and success, meeting physical and mental healthcare needs, promoting social and emotional development, supporting diversity and children's cultural needs, supporting permanency planning, ...

This paper presents a novel framework, called Bean, which aims to monitor, evaluate and enhance pre-school children’s skills and abilities through playing in Ambient Intelligence environments. The framework includes: (i) a model of children development based on the ICF-CY model and the Denver II assessment tool, aiming at early detection of children’s potential developmental issues to be furthe...

Enzymes containing flavin cofactors are predominantly involved in redox reactions in numerous cellular processes where the protein environment modulates the chemical reactivity of the flavin to either transfer one or two electrons. Some flavoenzymes catalyze reactions with no net redox change. In these reactions, the protein environment modulates the reactivity of the flavin to perform novel ch...

We tried to create an environment conducive to learning argumentation skills by combining collaborative use of case libraries with teacher facilitation of an appropriate kind. We present here the way we designed the environment, including the case library we created and the role of the teacher. The role of the case library in facilitating both collaboration and construction and evaluation of ar...

Use of simulations for design of systems requires assurance that the underlying modeling theories and simulation strategies are correctly realized. For example, not only it is crucial to employ modeling and simulation theories, but it is also critical to develop software architectures (environments) that guarantee correct implementation of simulation Model execution. In this paper, we will (i) ...