نتایج جستجو برای: il12
تعداد نتایج: 453 فیلتر نتایج به سال:
IBD: Inflammatory Bowel Disease ; UC: Ulcerative Colitis; CD: Crohn’s Diseases; TNF-α: Tumor Necrosis Factor α; IL12/23: Interleukin 12/23; IL-6R: Interleukin 6R; iRNA: information Ribonucleic acid; SC: Stem Cells; CT: Cell Therapy; MSC: Mesenchymal Stem Cells; HSC: Hematopoietic Stem Cells; 2,4,6-TNBA: 2,4,6-Trinitrobenzene Sulfonic Acid; SDF-1: Stromal Derived Factor-1; VEGF: Vasculoendotheli...
we have reviewed the medical records of 40 patients with disseminated (bacille calmette-guerin) bcg from 1996 to 1999 in the immunology department of the children hospital, medical center, tehran university. these patients are divided in to 3 groups: 1. patients who had disseminated (bacille calmette-guerin) bcg after vaccination and their diagnosis was chronic granulomatous disease. 2. patient...
PLAIN ENGLISH SUMMARY In the United Kingdom (UK), official bodies such as the Department of Health and research funders such as the National Institute for Health Research support and encourage lay involvement in all stages of research studies. The SHARED study has had substantial patient and public involvement (PPI) from developing the idea to dissemination. The aim of the study has been to dev...
The combined therapeutic potential of an immunocytokine designed to deliver IL-12 to the necrotic regions of solid tumors with an anti-PD-L1 antibody that disrupts the immunosuppressive PD-1/PD-L1 axis yielded a combinatorial benefit in multiple murine tumor models. The murine version of the immunocytokine, NHS-muIL12, consists of an antibody (NHS76) recognizing DNA/DNA-histone complexes, fused...
Safe and effective treatment of spontaneous neoplasms with interleukin 12 electro-chemo-gene therapy
Electroporation improves the anti-tumour efficacy of chemotherapeutic and gene therapies. Combining electroporation-mediated chemotherapeutics with interleukin 12 (IL-12) plasmid DNA produces a strong yet safe anti-tumour effect for treating primary and refractory tumours. A previously published report demonstrated the efficacy of a single cycle of IL-12 plasmid DNA and bleomycin in canines, an...
Impaired Cytokine Responses to Epstein-Barr Virus Antigens in Systemic Lupus Erythematosus Patients.
We analyzed cytokine responses against latent and lytic Epstein-Barr virus (EBV) antigens in systemic lupus erythematosus (SLE) patients and healthy controls (HCs) to obtain an overview of the distinctive immune regulatory response in SLE patients and to expand the previously determined impaired EBV-directed T-cell response. The concentrations of 14 cytokines (IL2, IL4, IL5, IL6, IL10, IL12, IL...
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