ttp://dx.doi.org/10.1016/j.jpge.2016.02.004 341-4545/© 2016 Sociedade Portuguesa de Gastrenterologia. Published C BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4 owel syndrome (IBS). The patient denied regular mediation or recent use of any drugs, namely antibiotics or on-steroidal anti-inflammatory drugs. Laboratory studies howed an increased C-reactive protein and a negative ...

BACKGROUND AND AIMS Experimental studies have shown that luminal bacteria may be involved in Crohn's disease. Probiotics are a possible alternative to antibiotics. The aim of this randomised placebo controlled study was to determine if Lactobacillus GG, given by mouth for one year, could prevent Crohn's recurrent lesions after surgery or to reduce their severity. METHODS Patients operated on ...

A 28-year-old man presented with anemia symptoms and intermittent tarry stool passage for three days. No stigmata of hemorrhage were identified using esophagogastroduodenoscopy, ileocolonoscopy, and contrast-enhanced computed tomography. He then developed massive tarry stool passage with profound hypovolemic shock and hypoxic respiratory failure. Emergent angiography revealed active bleeder, pr...

A 70-year-old patient presented with a 6-month history of bloating, flatulence, diarrhea and foul-smelling retching. He had undergone a Billroth II gastrectomy due to complicated peptic ulcer disease 30 years ago. Physical examination denoted mild abdominal distention. Laboratory tests revealed macrocytic anemia (Hb: 10.1 g/dL, MCV: 102 Fl) with severe vitamin B12 deficiency (161 pg/mL), althou...

Although ileocolonoscopy is the gold standard for diagnosis of inflammatory bowel disease and is useful for assessing the disease severity in the colon and terminal ileum, several alternative diagnostic techniques have been developed recently. For ulcerative colitis (UC), magnification colonoscopy, endocytoscopy, and confocal laser endomicroscopy enable assessment of histological inflammation w...

OBJECTIVE To investigate immune cells of the colonic mucosa and fecal short-chain fatty acids (SCFAs) in treatment-naive patients with a clinically isolated syndrome (CIS) or early relapsing MS. METHODS In this cross-sectional proof-of-concept study, we obtained mucosal specimens during ileocolonoscopy from 15 untreated patients with CIS/MS and 10 controls. Mucosal immune cells were analyzed ...

BACKGROUND Prevalence of Crohn's disease (CD) among patients with rheumatic illnesses in India is grossly under estimated, especially when it has overtaken that of Ulcerative Colitis in the West. AIM To study the frequency of histologically unequivocal CD amongst clinically suspected patients with enteropathic arthropathy and to ascertain if the arthritics with CD have any independent clinica...

BACKGROUND/AIMS Identifying predictors of endoscopic recurrence (ER) has become very important to guide the decision of postoperative strategy. This study aimed to determine the rate of endoscopic recurrence until 12 months after ileocolic resection for Crohn disease (CD) in a cohort and identify its possible predictors. MATERIALS AND METHODS We conducted a retrospective single-center study t...