We report herein a feasible study concerning syntheses and structure of some diazolium salts with dihydroxyacetophenone skeleton of anticipated anticancer activity. A fast, general and facile method for preparation of 1,3-diazol salts via N-alkylation reactions under conventional heating and microwave irradiation is presented. The microwaves remarkably accelerated these N-alkylations, the react...

A series of new and known bis(imidazolium) chloride and bromide salts bridged by either a methylene group (1−8, 10a,b) or an ethylene group (9a,b) and bearing different N substituents (Me, Et, Bn, tBu, Mes) have been reacted with [Fe{N(SiMe3)2}2]2 to yield the four-coordinate iron(II) complexes [LFeX2] (11−20; X = Cl, Br; L = chelating bis(imidazolylidene) ligand). Molecular structures of six o...

To determine the essential parameters for mesophase formation in imidazolium-based ionic liquids (ILs), a library of 1-alkyl-3-dodecylimidazolium bromides was synthesized, abbreviated as CnC12, where 0 ≤ n ≤ 13, as the general notion is that a dodecyl side chain would guarantee the formation of an ionic liquid crystal (ILC). All salts were fully characterized by NMR spectroscopy and mass spectr...

With a view to applications in bifunctional catalysis, a modular cross-coupling strategy has been used to prepare amine bis(imidazolium) salts (3a and 3b) and an amine mono(imidazolium) salt (6) as precursors to chelating amido-NHC ligands. Treating the pro-ligands 3 with 3 equivalents of the bulky base KHMDS and Pd(OAc)(2) or PtCl(2)(COD) gave the four amido bis(N-heterocyclic carbene) pincer ...

1 mimicking axial chirality, in which a chiral carbon center induces a preferred conformation 2a by rotation around an N–Ar bond which is fixed by formation of a chelate structure with metal (Fig. 1). In order to expand the scope of our chiral mimetic concept, we planned to develop a novel N-heterocyclic carbene ligand 3. The substituent R on the sp N group in the carbene ligand 3 may be confor...

We have designed imidazolium and piperazinium salts of pyropheophorbide-a in order to develop effective photosensitizers which have good solubility in polar and non polar media and to reveal the possible influences of the piperazine and imidazole moieties on the biological activities of pyropheophorbide-a. The phototoxicity of those pyropheophorbide-a salts against A549 cells was studied in vit...

We present a high yield synthesis of 1-ethyl-3-methyl-imidazole-2-chalcogenones from readily available imidazolium-2-carboxylate zwitterions NHC−CO2 and elemental chalcogens. In sharp contrast to previous syntheses for corresponding thiones selones imidazolium salts bases our reactions proceed fast with full instead low conversion selectivity, decarboxylation is the driving force. Furthermore, ...