Primary immune deficiency diseases (PIDDs) are a group of severe genetically determined caused by disorder the immunity links: humoral and cell-mediated links, phagocytosis, complement system. PIDDs characterized atypical recurrent infections, as well autoimmune oncological processes. In case clinical symptoms, skin manifestations in allow to suspect presence congenital disorders immunity. Ther...

mannose-binding lectin (mbl) is a protein of innate immune system that is involved in opsonization and complement activation. mbl deficiency is associated with predisposition to infectious diseases; however subnormal levels are also seen in healthy subjects. the aim of this study was to investigate the prevalence and clinical manifestation of mbl deficiency in patients with increased susceptibi...