The intravenous, intramuscular or intraperitoneal administration of water solubilized graphene nanoparticles for biomedical applications will result in their interaction with the hematological components and vasculature. Herein, we have investigated the effects of dextran functionalized graphene nanoplatelets (GNP-Dex) on histamine release, platelet activation, immune activation, blood cell hem...

on variations of streptococci as regards hemolysis and other characteristics, no complete and adequately controlled observations on the agglutination, agglutinin-binding, and agglutinogenic characteristics have been made, as far as we know, to determine whether variation in function has been associated with change in the antigenic constituents of the cocci. We are reporting, therefore, comparat...

In induction of systemic and mucosal immunity, particulate antigens are more effective than soluble antigens possibly because they are more efficiently endocytosed by mucosal-associated lymphoid tissue (MALT) M cells. In this study, we determined the systemic and mucosal immune responses in rabbits following intranasal immunization of tetanus toxoid TT and CpG-ODN encapsulated within PLGA nanos...

In induction of systemic and mucosal immunity, particulate antigens are more effective than soluble antigens possibly because they are more efficiently endocytosed by mucosal-associated lymphoid tissue (MALT) M cells. In this study, we determined the systemic and mucosal immune responses in rabbits following intranasal immunization of tetanus toxoid TT and CpG-ODN encapsulated within PLGA nanos...

BACKGROUND Autoimmune hemolytic anemia is a hematologic disorder that is rarely observed in infants and young children. Most of the cases are associated with viral or bacterial infections. In some cases, AIHA can be characterized by a chronic course and an unsatisfactory control of hemolysis, thus requiring prolonged immunosuppressive therapy. CASE REPORT Especially in children younger than 2...

By J. V. DAdE, M.B., M.R.C.P. LONDON H YDROGEN ion concentration has a controlling effect upon many hemolytic systems, both simple and complex. Osbor& in 1934 reviewed the early literature on the effect of pH on the hemolysis by complement of corpuscles sensitized by hemolytic immune body. He found that the optimum reaction for the hemolysis of sheep corpuscles by guinea pig serum was about pH ...

The content in hemolysin of a solution is commonly measured as the amount which is just sufficient to produce complete hemolysis of an arbitrary quantity of red blood cells, usually 0.5 cc. of a 5 per cent suspension of washed erythrocytes. The method employed for such measurement gives results which are neither exactly comparable in determinations made at different times, nor highly precise. T...

background: glucose-6-phosphate dehydrogenase (g6pd) deficiency is the most common enzyme disorder in human. the aim of this study was to determine the prevalence of g6pd deficiency among children and evaluate its association with abo/rh blood groups.   method: blood samples of 3401 asymptomatic children were analyzed and compared with 317 children who were admitted to hospital because of hemol...

background hemolyis of red blood cells is a serious toxic effect commonly found among patients envenomed by hemiscorpius lepturus scorpion. objectives the aim of the present study was to evlaute the efficay of the avaible polyvalent antivneom in preventing this phenomena. materials and methods using a red blood cell fragility test, the anti-hemolytic effectiveness of a new antivenom serum again...

The Elek test was modified for detection of the heat-labile enterotoxin of enterotoxigenic Escherichia coli. A total of 164 strains of E. coli were tested by the modified Elek test, and the results correlated well with those of the Chinese hamster ovary cell assay and passive immune hemolysis. It is concluded that the modified Elek test is a simple and reproducible assay method for identificati...