Declan P. Prendergasta,∗, M. Isla Hallidaya,∗∗, Neil V. McFerrana, Martin Curranb, Brian McIhattonb, Derek Middletonb, Mark T. Foxa and Andrew Wallacea Centre for Peptide and Protein Engineering, The Queen’s University of Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast, BT9 7BL, N. Ireland Northern Ireland Histocompatability and Immunogenetics Laboratory, Blood Transfusion Building, B...

both genetic and environmental factors seem to play role in the etiology of meniere's disease (md). several genes may be involved in susceptibility of md including human leukocyte antigens (hla). the associations between md and hla alleles have been previously studied in other populations and certain hla alleles were shown to be predisposing. the aim of this study was to determine the associati...

This review summarizes the previous and current literature on the immunogenetics of idiopathic inflammatory myopathy (IIM) and updates the research progress that has been made over the past decade. A substantial part of the genetic risk for developing adult- and juvenile-onset IIM lies within the major histocompatibility complex (MHC), and a tight relationship exists between individual human le...

The T-cell mediated autoimmune process that destroys pancreatic beta cells in type 1 diabetes (T1D) is a complex phenotype influenced by multiple genetic and environmental factors. Human leukocyte antigen (HLA) accounts for about half of the genetic susceptibility, through a large variety of protective and predisposing haplotypes. Other important loci associated with T1D, with much smaller effe...

1Division of Rheumatology and Immunogenetics, The University of Texas Health Science Center at Houston, Houston, Texas, USA 2Department of Rheumatology and Clinical Immunogenetics, The University of Texas Health Science Center at Houston, Houston, Texas, USA 3Department of Epidemiology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA 4Department of Medicine/ Rheumatolog...

IMGT, the international ImMunoGeneTics information system((R))(http://imgt.cines.fr) created in 1989, by the Laboratoire d'ImmunoGénétique Moléculaire (LIGM), Université Montpellier II and CNRS, Montpellier, France, is a high quality integrated information system, secialized in immunoglobulins (IG), T cell receptors (TR), major histocompatibility complex of human and other vertebrates and relat...

Hematology and Bone Marrow Transplantation Unit, Department of Oncology, San Raffaele Scientific Institute, Milano, Italy; Biostatistics Unit, Department of Health Sciences (DISSAL), University of Genova, Italy; Immunogenetics Laboratory, Unit of Immunohematology and Blood Transfusion, Division of Regenerative Medicine and Stem Cell Therapy, San Raffaele Scientific Institute, Milano, Italy; San...

The HLA Technologist and Director Certification Program for Histocompatibility Testing of the Japanese Society Immunogenetics (JSHI) offers various programs training opportunities members to be certified as expert. Here we will make comment on difficult questions from past paper tests help your study. In addition, medical ethics issues mentioned provide a learning opportunity.