Introduction. primary mucinous carcinoma of the eyelid skin is a rare adenocarcinoma glands. This tumor rarely metastasizes but frequently recurs. The study objective to describe clinical case skin, present macroscopic, histological and immunohistological descriptions this pathology. Clinical case. male, 66 years old, sought medical care due neoplasm lower eyelid. macroscopically subcutaneous n...

BACKGROUND Glioblastomas may develop de novo (primary glioblastomas, P-GBLs) or through progression from lower-grade astrocytomas (secondary glioblastomas, S-GBLs). The aim of this study was to compare the immunohistochemical classification of glioblastomas with clinically determined P-GBLs and S-GBLs to identify the best combination of antibodies for immunohistochemical classification. METHO...

INTRODUCTION It is well known that the use of a microwave oven greatly reduces the time for histoprocessing. OBJECTIVE Apply the microwave-based histoprocessing method "Fast Track Biopsy" (FTB), previously described for breast needle-core biopsies, to samples of other organs. METHODS From 01/09/2008 to 31/12/2008, 125 normal and neoplastic tissue samples (thickness from 0.2 and 1.2 cm) were...

Immunohistochemical (IHC) determination of receptor status in breast cancer patients is frequently inaccurate. Since it directs the choice of systemic therapy, it is essential to increase its reliability. We increase the validity of IHC receptor expression by additionally considering gene expression (GE) measurements. Crisp therapeutic decisions are based on IHC estimates, even if they are bord...

Trichogerminoma is a rare neoplasm which was first described in 1992 and there is still controversy over its inclusion into the spectrum of trichoblastoma. A 79-year-old woman presented with a 5-year history of an asymptomatic nodule on the left posterior neck. Histologically, the lesion revealed a well-demarcated deep dermal nodule surrounded by a pseudocapsule. The tumor was composed of lobul...

During the past years, many studies have shown that infrared spectral histopathology (SHP) can distinguish different tissue types and disease types independently of morphological criteria. In this manuscript, we report a comparison of immunohistochemical (IHC), histopathological and spectral histopathological results for colon cancer tissue sections. A supervised algorithm, based on the "random...

This study sought to establish health-care quality indicators based on data from routine clinical records produced by the Municipal Health Department in Maringá, Paraná State. Records for 7813 patients seen in the month of October 1991 at three Integrated Health Centers (IHC) were assessed to determine whether the recorded information allowed for the formulation of quality indicators. Indicator...

Introduction Melanoma is the most serious form of skin cancer, resulting in nearly 10,000 deaths per year in the US alone. Approximately 76,000 people are diagnosed with melanoma each year, and that number has been growing steadily over the last 30 years. Tragically, melanoma affects younger as well as older people. In fact, it is one of the most common forms of cancer in people younger than 30...

This article presents the construction of scaffolds composed polylactic acid (PLA) with different concentrations hydroxyapatite (HA) by electrospinning, which were superficially modified polypyrrole (PPy/I) plasma polymerization. A preliminary study was conducted biological and mechanical behavior when they implanted in back rabbits for 30 days; bone cells differentiated from mesenchymal stem (...

Abstract Galactoceles are benign lesions formed at the expense of breast glandular tissue. Its occurrence in boys is exceptional, with isolated reports scientific literature. We present case a 2-year-old boy who debuted unilateral enlargement 18 months evolution, no other associated symptoms. Initial hormonal study showed alterations. Ultrasonography presence homogeneous 5-cm retroareolar cyst....