Oral verrucous carcinoma (VC) is a rare locally invasive tumor. The histopathological diagnosis of verrucous carcinoma should be accompanied with careful identification of tumors with a greater chance to become frank cancers. A comprehensive Google and PubMed search was carried out using “oral, verrucous carcinoma and immunohistochemistry” as the key searching terms. All the articles till date ...

Brachyury is a transcription factor which is required for posterior mesoderm formation and differentiation as well as for notochord development during embryogenesis. Due to its expression in the neoplastic cells of chordoma, a malignant tumour deriving from notochordal remnants, but not in tumors showing a similar histology, brachyury has been proposed as a diagnostic marker of this neoplasia. ...

CONTEXT Malignant neural sheath tumors of the trigeminal nerve affecting the nasal cavity and the paranasal sinuses are extremely rare. With conventional optical microscopy, their identification is difficult, and it is necessary to confirm them by means of electron microscopy and immunohistochemical techniques. CASE REPORT The patient was a 41-year-old woman with a ten-month progressive histo...

Indirect immunohistochemistry (IHC) on skin biopsies for identification of persistently infected (PI) animals has been used as a parallel test to antigen and antibody ELISAs in a bovine viral diarrhoea (BVD) voluntary control program. The aim was to evaluate the reliability and feasibility of IHC on ear skin tissues to detect PI animals in field conditions, including both adult and calves under...