Vulval involvement in Crohn's disease (CD) is rare, particularly in children. The clinical features include erythema, edema, ulceration, and labial skin tags. The authors present two cases of children with vulval CD. In both cases, marked labial edema was the presenting feature. In one patient the immunomodulator tacrolimus ointment 0.03% was used with success. In the second patient control was...

The situation with the COVID-19 pandemic in world is still tense. Due to peculiarities of its pathogens, there a low efficiency use available specific etiotropic drugs, which leads need search for new active means combating this dangerous infectious disease. Since function T-cell immunity significantly impaired COVID-19, it advisable find out effect correcting part immune response on course cor...