نتایج جستجو برای: immunoregulatory activity
تعداد نتایج: 1137202 فیلتر نتایج به سال:
Withania somnifera an Indian traditional medicinal herb, is known to possess antistress, antioxidant, analgesic, anti-inflammatory, cardioprotective, adaptogenic, antispasmodic, immunomodulatory and immunostimulant activities. Its other activities include anti-inflammatory, immunoregulatory, anti-tumor, anti-angiogenic, antiinvasive and chemopreventive effects. We investigated the antioxidant, ...
Concanavalin A (Con A)-treated peripheral blood lymphocytes from healthy volunteer donors have been shown to suppress proliferative responses associated with thymus-derived lymphocytes (T-cells). The present investigations demonstrate that peripheral blood lymphocytes incubated with Con A for 48 hr can abrogate pokeweed mitogen-stimulated differentiation of bone-marrow-derived (B) lymphocytes t...
Due to their ability to inhibit antigen-induced T cell activation in vitro and in vivo, anergic T cells can be considered part of the spectrum of immunoregulatory T lymphocytes. Here we report that both murine and human anergic T cells can impair the ability of parenchymal cells (including endothelial and epithelial cells) to establish cell: cell interactions necessary to sustain leukocyte migr...
We have recently reported that interleukin (IL)-15 and IL-2, which signal through IL-2Rbetagamma, oppositely regulate expression of the proinflammatory chemokine receptor CX3CR1. Here we delineate molecular mechanisms responsible for this paradox. By using a luciferase reporter plasmid, we identified a 433-bp region spanning the major transcriptional start point of human CX3CR1 that, when expre...
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