نتایج جستجو برای: immunostimulatory activity

تعداد نتایج: 1135910  

Journal: :Proceedings of the National Academy of Sciences 1992

Journal: :European journal of immunology 2010
Esther Tamayo Jorge Postigo Jovanna González Maigualida Fernández-Rey Marcos Iglesias Inés Santiuste Carlo Riccardi Rino Rappuoli Giuseppe Del Giudice Ramón Merino Jesús Merino

The Escherichia coli heat-labile enterotoxin (LT) possesses a powerful mucosal and systemic adjuvant effect. However, little is known about the cellular and molecular basis of the immunostimulatory activity of LT at the mucosal level, and even less information is available on the mechanisms underlying its systemic adjuvant activity. In this study, we show that distinct mechanisms are responsibl...

Journal: :Oncology reports 2011
Jin Wang Wanggang Zhang Aili He Wanhong Zhao Xingmei Cao

Acute lymphoblastic leukemia (ALL) is a common malignant disease and a major cause of mortality due to recurrent disease. Immunotherapy is a promising strategy for eradicating minimal residual disease and thus preventing the relapse of leukemia. Apart from stem cell transplantation, CpG oligodeoxynucleotides (ODNs) are excellent candidates for the immunotherapy of leukemia. However, the number ...

Journal: :Proceedings of the National Academy of Sciences 1983

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