To generate a model of mammalian karyotype evolution and to extend our knowledge of the evolutionary relationships of mammals, it is helpful to deduce ancestral chromosomal arrangements. Of particular interest would be a global comparison among the 3 major extant groups of mammals, since this would reveal the most ancient arrangements of the mammalian genome and allow us to follow chromosomal r...

Developing ordered gene maps from multiple mammalian species coupled with chromosome-painting data provide a powerful resource for resolving the evolutionary history of chromosomes and whole genomes. In this work, we recapitulate the evolutionary history of human chromosome 1 and its homologs in placental mammals, putatively the largest physical unit in the ancestral placental genome. Precise d...

Chromosome 'painting' refers to the hybridization of fluorescently labeled chromosome-specific, composite probe pools to cytological preparations. Chromosome painting allows the visualization of individual chromosomes in metaphase or interphase cells and the identification of both numerical and structural chromosomal aberrations in human pathology with high sensitivity and specificity. In addit...

Background: Various factors, like pregnancy, can lead to irregular sleep patterns. Sleep disturbances are common during pregnancy, potentially leading to adverse maternal and neonatal outcomes. Therefore, this study aimed to examine the effectiveness of art therapy based on painting on sleep quality of pregnant women in the third trimester. Methods: This quasi-experimental study followed by a ...

Full-body, unencumbered, gestural interfaces o er new possibilities for computer painting tools. However, traditional painting metaphors and current gestural input technology are not well suited to one another; the user cannot be tracked with su cient accuracy to support brush-like or pen-like painting. Our approach to this problem has been to interpose di erent layers of abstraction between in...

Although quite many qualitative studies on painting in Alzheimer’s disease (AD) have been conducted, there is a lack of quantitative studies, examining the ability to paint in people with AD in relation to disease stages, and to what extent instructions are associated with actual performance. The present study aimed at investigating the capability to paint among nonartist AD participants (N = 1...

To test quantitatively whether there are systematic chromosome-chromosome associations within human interphase nuclei, interchanges between all possible heterologous pairs of chromosomes were measured with 24-color whole-chromosome painting (multiplex FISH), after damage to interphase lymphocytes by sparsely ionizing radiation in vitro. An excess of interchanges for a specific chromosome pair w...

The relationship between the activity of painting and performance of stereotyped and other stress-related behaviour was investigated in four captive Asian elephants at Melbourne Zoo, Australia. The activity involved the elephant being instructed to paint on a canvas by its keeper in front of an audience. Painting by elephants in zoos is commonly believed to be a form of enrichment, but this ass...