patients with solitary rectal ulcer syndrome (srus) come to a physician with passage of mucus and bloody liquid within defecation. the treatment for srus is depended to the severity of symptoms and the existance of rectal prolapse. this study is a report of the assessing of rectopexy as surgical modalities for 62 medical treatment resistant srus patients who were referred to the gastrointestina...

The aim of the present study was to investigate the effect of Bifidobacterium animalis subsp. lactis, BB-12®, on two primary end points - defecation frequency and gastrointestinal (GI) well-being - in healthy adults with low defecation frequency and abdominal discomfort. A total of 1248 subjects were included in a randomised, double-blind, placebo-controlled trial. After a 2-week run-in period,...

BACKGROUND Constipation is a significant problem in the elderly, specifically nursing home and/or extended-care facility residents are reported to suffer from constipation. Lactic acid bacteria (LAB) are beneficial probiotic organisms that contribute to improved nutrition, microbial balance, and immuno-enhancement of the intestinal tract, as well as diarrhea and constipation effect. The objecti...

Poor sanitation remains a major public health concern linked to several important health outcomes; emerging evidence indicates a link to childhood stunting. In India over half of the population defecates in the open; the prevalence of stunting remains very high. Recently published data on levels of stunting in 112 districts of India provide an opportunity to explore the relationship between lev...

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BACKGROUND Cauda equina syndrome (CES) is a rare neurologic complication of lumbar herniated disc for which emergency surgical decompression should be undertaken. Despite the common belief that the restoration of functions that are affected by CES can take several years postoperatively, follow up seldom exceeds the first year after surgery. Long term outcome of especially micturition, defecatio...

BACKGROUND Previous studies demonstrated that constipation and painful defecation are associated with stool toileting refusal (STR), but whether they are the result of STR or occur before this behavior is not known. OBJECTIVE To determine whether constipation and painful defecation occur as a result of STR or occur before STR. METHODS Three hundred eighty children between 17 and 19 months o...

Caenorhabditis elegans defecation is a rhythmic behavior, composed of three sequential muscle contractions, with a 50-s periodicity. The motor program is driven by oscillatory calcium signaling in the intestine. Proton fluxes, which require sodium-proton exchangers at the apical and basolateral intestinal membranes, parallel the intestinal calcium flux. These proton shifts are critical for defe...

Pathogen expulsion from the gut is an important defense strategy against infection, but little is known about how interaction between the intestinal microbiome and host immunity modulates defecation. In Drosophila melanogaster, dual oxidase (Duox) kills pathogenic microbes by generating the microbicidal reactive oxygen species (ROS), hypochlorous acid (HOCl) in response to bacterially excreted ...

Stunting is a nutritional problem in Indonesia that cross-sectoral due to its complex and multifactor causal factors. The government has role of involvement capacity stunting reduction interventions. One the determinants Aceh Singkil District open defecation which an indicator WASH (Water, Sanitation, Hygiene) contributes incidence inflammatory diseases. This study aims analyze determinant with...