common itl hemolytic anemia. In a case described by Baty,’ the reticulocytes numbered 92 per cent. There is no completely satisfactory explanation of the nature of hemolytic crisis, nor of the mechanisms responsible for the recovery phenomenon. Lepel2 and Dameshek and Schw-art.z3 pointed out the similarity betw-eetl the various phenomena observed in the hemolytic anemia of humans w-ith those ob...

Hemolytic uremic syndrome (HUS) is one of the common causes of acute renal failure in children and is characterized by microangiopathic hemolytic anemia and thrombocytopenia. About 5% to 10% of all HUS cases in children are non-diarrheal HUS (atypical HUS) [1,2]. Many triggering causes of atypical HUS, such as non-enteric infections, viruses, drugs, systemic diseases, glomerulopathies, malignan...

glucose-6-phosphate dehydrogenase (g6pd) deficiency is the most prevalent enzymopathy in mankind. it has sex-linked in­heritance. this enzyme exists in all cells.  g6pd deficiency increases the sensitivity of red blood cells to oxidative dam­age. g6pd deficiency was discovered in 1950 when some people suffered hemolytic anemia as a result of taking antimalar­ial drugs (primaquin). most people w...

The kinetics of the hemolytic reaction effected by the hemolysin of Clostridium septicum, strain 44, has been studied with regard to the effect of concentration, temperature, and hydrogen ion concentration on the rate of the hemolytic reaction. The kinetics of hemolysis was found to resemble in several respects that of enzyme-catalyzed reactions, but differed in the absence of a clearly defined...

In our initial immunochemical study of the red blood cell (RBCI membrane proteins targeted in 20 cases of warmantibody autoimmune hemolytic anemia (AHA), RBC eluates of 6 patients mediated immunoprecipitation (IP) of both band 3 and glycophorin A (GPA). This dual IP pattern had previously been observed with murine monoclonal antibodies (MoAbs) against the high frequency blood group antigen, Wrb...

OBJECTIVE To report a rare side effect of metformin, an oral antidiabetic drug that is used for the treatment of type 2 diabetes mellitus. CLINICAL PRESENTATION AND INTERVENTION A 17-year-old boy was hospitalized for receiving acute lymphoblastic leukemia treatment that was composed of vincristine, L-asparaginase, daunorubicin, and prednisone. Hyperglycemia was determined without any clinical...

The interaction between antibodies and the surface antigens of infectious bursal disease virus particles was studied in the agarose gel by using single radial hemolysis (SRH) test. Sonicated antigen was used to sensitize the Human "O" erythrocytes. Hemolytic zones, using the filter paper discs were observed after overnight incubation in humid chamber at 37C. Indirect Hemagglutination (IHA) and ...

Venom phospholipases A2 (PLA(2)) are associated with neurotoxic, myotoxic, cardiotoxic, platelet aggregation, and edema activities. A PLA(2) (Drs-PLA(2)) was purified from Daboia russelii siamensis venom by a two-step purification procedure consisting of size-exclusion, followed by anion exchange high performance liquid chromatography (HPLC). The molecular weight of the Drs-PLA(2) was 13,679Da,...

Technetium-99m (Tc) has been the radionuclide of choice for nuclear medicine procedures and experimental research. Because of its optimal nuclear properties, Tc is suitable for high efficiency detection with the advantage of reduced radiological waste. Crotalus venom (CV) has been shown to reduce tumors in clinical studies and tissue distribution studies are very important for clinical use. The...