Erythromycin and clindamycin are major alternatives to βlactam antibiotics. Bacterial resistance to macrolide and lincosamide antibiotics is increasing worldwide. Erm genes express either constitutive macrolide, lincosamide streptogramin B resistance phenotype (cMLSB) or inducible phenotype (iMLSB) and msrA gene expresses (MSB) phenotype. The aim of this study was to determine the frequency of ...

The widespread use of Macrolide Lincosamide Streptogramin B (MLSB) antibiotics has led to an increase in the resistant strains. Although Clindamycin is effective against MRSA but its use in the presence of Erythromycin can lead to induction of cross-resistance among members of the MLSB group which could limit the effectiveness of this drug. Furthermore, at times, some strains are also harbored ...

Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of both nosocomial and community-acquired infections. We describe an outbreak caused by the MRSA Pediatric clone expressing an unusual lincosamide resistant phenotype. Between January and May 2006, an MRSA outbreak was detected at the Neonatal Unit of Hospital Interzonal General de Agudos "Evita", Buenos Aires Province, Argenti...