Aims: To compare the effects of Hyaluronic acid (PerioKIN 1%)® and ozonated oil (O3OHEAL-M) ® on healing after induced wounds in rabbits oral mucosa to detect presence interleukin-6 (IL-6) as a biomarker using immunohistochemistry. Materials methods: The study was conducted (12) male New Zealand rabbits, randomly divided into two groups (6 animals per group) according periods (3rd,7th, 14th) da...

Sulphur mustard (SM) is a well-known chemical warfare agent. It was first used during World War I and more recently in the Iran/Iraq conflict causing more than 100,000 Iranian casualties. Previous study showed that this gas can raised inflammatory marker but in this current case that suffered from cancer. After examine current case for candidate CABG, we found that Hs-CRP and IL-6 was very low ...

BACKGROUND The plasma level of cystatin C is a better marker than plasma creatinine for successful aging. It has been assumed that the advantage of cystatin C is not only due to it being a better marker for glomerular filtration rate (GFR) than creatinine, but also because an inflammatory state of a patient induces a raised cystatin C level. However, the observations of an association between c...

Introduction. Mean platelet volume (MPV) has been thought as a useful index of platelet activation. It is supposed that MPV is also associated with several inflammatory and infectious diseases. Korea still has a high incidence of tuberculosis (TB). The aim of this study was to investigate MPV as an inflammatory marker in TB patients. Materials and Methods. MPV were determined in 221 patients wi...

Depressive disorders are more common among persons with chronic diseases such as inflammatory bowel disease and anti-inflammatory effect of some antidepressants such as amitriptyline has been reported. Acetic acid colitis was induced in both reserpinised (depressed) and non-reserpinised (normal) rats. Reserpinised groups received reserpine (6 mg/kg, i.p.) one hour prior to colitis induction. Th...

Aim: The purpose of this study is to investigate the incidence, distribution and risk factors of cerebral microbleeds (CMBs) and the relation between CMBs and inflammation in ischemic cerebrovascular disease. Methods: Two hundred and one patients without acute infarction or transient ischemic attack were enrolled. The presence and number of CMB were assessed on susceptibility-weighted imaging. ...

Chitotriosidase (CHIT1) belongs to chitinase family. So far this enzyme has been the best investigated human chitinase regarding its biological activity and association with various disorders. In a healthy population, CHIT1 activity is very low and originates in the circulating polymorphonuclear cells. Conversely, during the development of acute/chronic inflammatory disorders, the enzymatic act...

BACKGROUND Resistin, a plasma protein, induces insulin resistance in rodents. Recent reports suggest that circulating levels of resistin are elevated in obese and insulin-resistant rodents and humans. Whereas rodent resistin is made in adipocytes, macrophages are a major source of human resistin. Given the convergence of adipocyte and macrophage function, resistin may provide unique insight int...