In recent years, clinicians are beginning to utilise Mobile Health Systems (mobile devices with clinical applications) when delivering healthcare services to patients at the point-of-care. For Mobile Health Systems (MHS) to be truly valuable, it is argued that the technological artefact be utilised post-adoption and embedded within the clinicians’ work practices. Infusion is a post-adoptive pha...

Purpose – The purpose of this paper is to investigate the effects of user competence on two different usage variables related to information systems (IS) infusion: explorative use and exploitative use. Design/methodology/approach – Structural equation modeling is used to construct a predictive model of user competence toward IS infusion. Individuals’ responses to questions about attitude and in...

OBJECTIVE During partial nephrectomy, renal hypothermia has been shown to decrease ischemia induced renal damage which occurs from renal hilar clamping. In this study we investigate the infusion rate required to safely cool the entire renal unit in a porcine model using retrograde irrigation of iced saline via dual-lumen ureteral catheter. MATERIALS AND METHODS Renal cortical, renal medullary...

BACKGROUND This study has compared the predictive performance of four pharmacokinetic models, two of which are currently incorporated in commercial target-controlled infusion pumps for the administration of propofol. METHODS Arterial propofol concentrations and patient characteristic data were available from nine patients who, in a published study, had received a standardized infusion of prop...

by producing reactive oxygen and nitrogen species, metal-induced toxicity and carcinogenicity alter dna bases, increase  lipid peroxidation, and change calcium and sulfhydryl homeostasis. the purpose of the study was to investigate putative effects of lemon balm and cinnamomum zeylanicum on the blood markers of welding workers. we measured nickel and chromium levels, biochemical parameters, blo...

This paper presents a lumped-parameter model that can reproduce blood volume response to fluid infusion. The model represents the fluid shift between the intravascular and interstitial compartments as the output of a hypothetical feedback controller that regulates the ratio between the volume changes in the intravascular and interstitial fluid at a target value (called "target volume ratio"). T...

Objective- To evaluate the total toxic dose of lidocaine and serum lidocaine concentrations resulting in clinical signs of toxicity in chickens. Design- Experimental study Animals- Eight healthy, female, 55-week-old chickens (Lohman breed) weighing 1.45 ± 0.17 kg (mean ± SD) Procedure- A loading dose of 2% lidocaine (4 mg/kg) was administered IV, followed by a constant-rate infusion at a dose o...

The most common approach for estimating substrate rate of appearance (R(a)) is use of the single-pool model first proposed by R. W. Steele, J. S. Wall, R. C. DeBodo, and N. Altszuler. (Am. J. Physiol. 187: 15-24, 1956). To overcome the model error during highly non-steady-state conditions due to the assumption of a constant volume of distribution (V), two strategies have been proposed: 1) use o...