zhumeria majdae is a rare an endemic medicinal plantspecies grown wild in iran. the hydro distilled essential aerial part oil of z. majdae analysed by gc–ms. thirty-one compounds representing 95.36% of the aerial part oil, respectively, were identified, of which linalool (48.14%), camphor (20.71%), limonene (4.83%), trans-linalool oxide (2.69%), 3-octanone (2.34%), terpinene-4-ol (2.30%), camph...

there is a growing concern about the application of molecular methods in epidemiological studies of infectious diseases. the objective of this study was to determine the genetic stability of methicillin resistance genes in staphylococcus aureus for the evaluation of resistance strain distribution. one hundred and fifteen s. aureus isolates from patients with staphylococcal infection were collec...

conclusions the results indicate that multidrug-resistant (mdr) strains of salmonella are increasing in number, and fewer antibiotics may be useful for treating s. enterica infections. routine investigation and reporting of antibiotic mics in patients presenting with salmonella infections is suggested. results of the total 19 salmonella spp. isolates recovered by the bactec automated system, al...

abstract: essential oils are commonly used to treat minor health problems. in this study the chemical compositions of lavandula officinalis and thymus vulgaris were determined by gas chromatography and mass spectrometry. gc/ms analysis of t. vulgaris resulted in thymol as the major oil component where as methyl sulfony exhibited as the most abundant constituent of l. officinalis. the antibacter...

background and aim: in recent years, due to the indiscriminate and irrational use of synthetic drugs, the resistance of pathogenic microorganisms has increased; therefore, new compounds are vitally needed. the purpose of this study was to investigate the effect of ethanolic and aqueous extracts of berberis vulgaris on escherichia coli, klebsiella pneumoniae, proteus mirabilis, citrobacter frund...

Background and Aim: There are some rich sources of antifungals in medicinal herbs. They have general acceptance due to their low cost and insignificant side effects. The efficacy of Peganum harmala (P. harmala) extract against Candida species was investigated in this study.    Materials and Methods: In this in vitro study, we used the maceration technique to obtain P. harmala aqueous and al...

The resazurin assay utilising microtitre-plate, described by Drummond and Waigh in 2000, has been modified to achieve more accuracy in the determination of the minimum inhibitory concentration (MIC) values of natural products, including crude extracts, chromatographic fractions or purified compounds against various bacterial strains. This modified resazurin method is simple, sensitive, rapid, r...

A series of benzofuran derivatives were designed and synthesized, and their inhibitory activites were measured against the SIRT1-3. The enzymatic assay showed that all the compounds showed certain anti-SIRT2 activity and selective over SIRT1 and SIRT3 with IC50 (half maximal inhibitory concentration) values at the micromolar level. The preliminary structure-activity relationships were analyzed ...