Real-world solids, such as rocks, soft tissues and engineering materials, are often under some form of stress. Most real materials also, to degree, anisotropic due their microstructure, a characteristic called the ‘texture anisotropy’. This anisotropy can stem from preferential grain alignment in polycrystalline aligned micro-cracks or structural reinforcement, collagen bundles biological tissu...

BACKGROUND The optimal initial noninvasive diagnostic testing strategy for stable coronary artery disease (CAD) is unknown. Although American guidelines recommend an exercise stress test as the first-line test, European guidelines suggest that stress imaging (myocardial perfusion imaging or stress echocardiography) or coronary computed tomography angiography may be preferable. Understanding the...

The effectiveness of initial low oxygen stress (ILOS) to control apple scald without postharvest application of scald inhibitors and fungicides was investigated. Scald susceptible (‘Granny Smith’, ‘Law Rome’, ‘Red Delicious’) and not susceptible (‘Idared’) fruits were harvested preclimacterically and treated at 1°C with (1) ILOS pretreatment or (2) no pretreatment as control. Fruit were then st...

abstract diabetes mellitus is one of the major metabolic disorders. diabetes is recognized for severe complications including diabetic nephropathy, neuropathy and retinopathy. long-lasting effect of hyperglycemia results in increased oxidative stress. oxidative stress results from an imbalance between radical-generating and radical scavenging systems. increased oxidative stress has been shown t...

In this paper, a two-dimensional computational model is proposed for predicting the initiation position and propagation path of subsurface crack of spur gear tooth flank. In order to simulate the contact of teeth, an equivalent model of two contacting cylinders is used. The problem is assumed to be under linear elastic fracture mechanic conditions and finite element method is used for numerical...

We observed increased lung thallium-201 (201T1) activity on initial stress myocardial images in patients with coronary artery disease (CAD). To assess the clinical significance of this finding, initial and 2hour delayed 201T1 images were stored in a computer immediately after supine stress testing in 49 patients (39 with CAD and 10 controls). Regions of interest over the heart and lung were sel...

The axon initial segment (AIS), the domain responsible for action potential initiation and maintenance of neuronal polarity, is targeted for disruption in a variety of central nervous system pathological insults. Previous work in our laboratory implicates oxidative stress as a potential mediator of structural AIS alterations in two separate mouse models of central nervous system inflammation, a...