NCI-NHGRI Working Group on Replication in Association Studies The study of human genetics has recently undergone a dramatic transition with the com­ pletion of both the sequencing of the human genome and the mapping of human haplo­ types of the most common form of genetic variation, the single nucleotide polymorphism (SNP). In concert with this rapid expansion of detailed genomic information, c...

The 2 major cellular lipid species, sterols and fatty acids, have many roles in physiology. Not only are they essential structural components of eukaryotic cell membranes, but they are also used as sources for cellular energy, serve as precursors for biosynthesis of key cellular macromolecules, are strategically used as post-translational modifications of many proteins, and function as signalin...

NCI-NHGRI Working Group on Replication in Association Studies The study of human genetics has recently undergone a dramatic transition with the com­ pletion of both the sequencing of the human genome and the mapping of human haplo­ types of the most common form of genetic variation, the single nucleotide polymorphism (SNP). In concert with this rapid expansion of detailed genomic information, c...