objectives: the aim of this study was to compare of waist circumference with metabolic syndrome ,as a predictor insulin resistance in agroup of elderly population. methods & materials: in a cross-sectional study among 225 elderlyaged 60 year old and more whose clinical data were complete, 94 subjects (42 males and 52 females) who were able to sign the consent form mini mental stat examination>2...

Background and aim: Acanthosis nigricans (AN) is characterized by hyperpigmented velvety plaques of body folds and neck. Insulin can have a role in the pathogenesis of this disease and hyperinsulinemia as a consequence of insulin resistance may stimulate the formation of the characteristic plaques of AN. In this study insulin resistance was compared in obese women with and without AN.</sp...

retinol binding protein4 (rbp4) such as adipocytokines that could be a marker for type 2 diabetes and seems to be leading to increased insulin resistance. the purpose of this study was to evaluate the effect of aerobic training on serum rbp4 and insulin resistance in adult male rats. in the present experimental study 16 wistar rats were randomly divided to one of the exercise group (n=10) or co...

Background and objectives: The role of genetic components in expression of proteins involved in signaling pathways of fat and carbohydrate metabolism has been well-demonstrated. The aim of this study was to determine effects of high intensity interval training (HIIT) on glucose, insulin, and insulin resistance levels as well as IRS1 expression in gastrocnemius muscle of obese Wistar rats. Meth...

retinol binding protein4 (rbp4) is a type of adipokine which transports vitamin a to serum. rbp4 could be a bridge between obesity and insulin resistance. this study aimed to investigate the effects of aerobic exercises on rbp4 serum's concentration and metabolic syndrome risk factors in obese women.twenty obese women with body max index 35.81±3.67kg/m2, fat percentage 43.98±4.02, and waist to ...

background: insulin resistance has an important role in pathophysiology of polycystic ovarian syndrome (pcos). yet there are certain controversies regarding the presence of insulin resistance in non-obese patients. objective: the aim was to compare the insulin resistance and various endocrine and metabolic abnormalities in obese and non-obese pcos women.materials and methods: in this cross-sect...

background: insulin receptor substrate (irs) type 1 is a main substrate for the insulin receptor, controls insulin signaling in skeletal muscle, adipose tissue, and the vascular, so it is an important candidate gene for insulin resistance (ir). we aimed to compare the  effects of the dietary approaches to stop hypertension (dash) and usual dietary advices (uda) on irs1 gene expression in women ...

Background and Aim: The aim of this study was to investigate the effects of vitamin D supplementation during progressive resistance training on insulin resistance, blood lipids and body fat percentage in T2D men with vitamin D deficiency. Methods: Forty-eight men with T2D participated in the study voluntarily and were randomly assigned to 4 groups (n=12) including, resistance training (RT), vi...