نتایج جستجو برای: intensive therapy
تعداد نتایج: 770361 فیلتر نتایج به سال:
OBJECTIVES Our objective was to determine the timing of benefit with intensive statin therapy after an acute coronary syndrome (ACS) in two time windows: an early window soon after an ACS and a late window in more stable patients. BACKGROUND The Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22 (PROVE IT-TIMI 22) trial showed that the use of...
BACKGROUND Intensive insulin therapy has been found to reduce mortality in some critically ill patients. We performed a systematic review and meta-analysis to ascertain the effect of intensive insulin therapy on the incidence of acute kidney injury (AKI) in adult critically ill patients. METHODS We searched MEDLINE, SCOPUS and the Cochrane Central Register of Controlled Trials for studies tha...
BACKGROUND Type 1 diabetes mellitus is associated with an increased risk of cardiovascular disease (CVD) that is not fully explained by conventional risk factors. The Diabetes Control and Complications Trial (DCCT) showed that intensive diabetes therapy reduced levels of LDL cholesterol and triglycerides but increased the risk of major weight gain, which might adversely affect CVD risk. The pre...
CONTEXT A recent meta-analysis demonstrated that statin therapy is associated with excess risk of developing diabetes mellitus. OBJECTIVE To investigate whether intensive-dose statin therapy is associated with increased risk of new-onset diabetes compared with moderate-dose statin therapy. DATA SOURCES We identified relevant trials in a literature search of MEDLINE, EMBASE, and the Cochrane...
Neuropathy among the diabetes control and complications trial cohort 8 years after trial completion.
OBJECTIVE To evaluate the impact of prior intensive diabetes therapy on neuropathy among former Diabetes Control and Complications Trial (DCCT) participants. RESEARCH DESIGN AND METHODS At the conclusion of the DCCT, subjects in the intensive group were encouraged to maintain intensive therapy, and subjects in the conventional group were encouraged to begin intensive therapy. Thereafter, we a...
BACKGROUND We planned to investigate the effect of preoperative short period intensive physical therapy on lung functions, gas-exchange, and capacity of diffusion, and ventilation-perfusion distribution of patients with non-small cell lung cancer. METHODS Sixty patients with lung cancer, who were deemed operable, were randomly allocated into two groups. Intensive physical therapy was performe...
AIM To find out the difference between intensive insulin therapy and conventional insulin therapy in influencing the increase of superoxide dismutase (SOD), decrease of cytokine production (TNF-alpha and IL-6), increase of albumin level, and occurrence of SIRS. METHODS The study design was randomized pre and post control group design involving 40 adult patients admitted to the ICU of Sanglah ...
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