Determinar el efecto de las citocinas interleucinas (IL)4 y 10, interferon (IFN-Y) factor necrosis

the objective of this research was to investigate the influence of the over-expression of recombinant interferon-g during high cell density cultivation on cellular characteristics of recombinant e. coli. batch and fed-batch culture techniques were employed to grow escherichia coli bl21 for production of human gamma-interferon in pet expression system. final cell densities in batch and fed-batch...

conclusions office workers with chronic hepatitis c, treated with pegylated-interferon-α2b plus ribavirin, had work performance loss. in subjects treated with acetyl-l-carnitine supplementation we observed increased daily activity and reduced presenteeism and fatigue. acetyl-l-carnitinegroup had a smaller reduction of productivity comparing to placebo group. results significant difference were ...

objective: chronic infection of hepatitis b and hepatitis c are considered as the most important infectious diseases, which lead to drastic consequences such as liver dysfunction. depression is a psychiatric disorder which is concomitantly present in these patients, and decreases the patients’ quality of life. it may lead to suicide, homicide or intentional transmission of infectious to others....

Background: High dose Interferon Beta and Fingolimod are efficient in Multiple Sclerosis. Objectives: Comparison the efficacy of these two drugs in patients with treatment failure on low dose interferon beta. Materials and Methods: The MS patients (McDonald criteria 2010) with the history of unbeneficial treatment on low dose interferon beta participated in this randomized clinical trial ...

Vitiligo is a relatively common, acquired depigmenting disease caused by the loss of epidermal melanocytes. Oxidative stress known to participate in initiation vitiligo triggering autoimmunity. In this study, we tried identify factors serving as bridge between oxidative and autoimmunity vitiligo. According RNA sequencing analysis on H2O2-treated melanocytes, interferon-stimulated gene 15 (ISG15...

We report 3 cases of suicide attempts in postoperative patients with renal cancer after alpha interferon withdrawal. In the first patient, depression occurred during interferon therapy, and remained after interferon withdrawal. A suicide attempt occurred 7 months after interferon withdrawal. In the second and third patients, depression did not occur during interferon therapy, but suicide attemp...