Background: Interleukin 17 (IL-17) is pro-inflammatory cytokine that plays a crucial role in spondyloarthritis via the Th17/IL-17 axis. (1) Objectives: We aimed to study diagnosis value of IL-17 serum spondyloarthritis. Methods: conducted case-control study, including 104 subjects divided into 2 groups: -G1: 52 patients meeting Assessment SpondyloArthritis International Society (ASAS) criteria ...

BACKGROUND: Psoriasis is frequently accompanied by metabolic syndrome. Effect of anti-tumor necrosis factor therapies on increases in body weight well-known. Data the effects interleukin-17 inhibitors are limited. Authors determined effect anti-interleukin-17 composition and serum lipid inflammatory parameters among severe psoriatic patients. METHODS: Thirty-five patients were enrolled. Twenty-...

Background: Dendritic cells (DC) are a key regulator of the immune response, and interferon- beta (IFN-β) is considered an immunomodulatory molecule for DC. Objective: The purpose of this study was to evaluate the ability of IFN-β treated DC to induce cytokine secretion by CD4+ T cells. Methods: Dendritic cells were generated from blood monocytes with granulocyte-monocyte colony-stimulating fac...

There is increasing evidence that an exaggerated accumulation of activated neutrophils is linked to the clinical course of obstructive airway diseases, such as asthma and chronic obstructive pulmonary disease. The present review article focuses on the evidence that the T cell cytokine interleukin (IL)-17 plays a role in orchestrating the accumulation and subsequent activation of neutrophils in ...